Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1893209..1893349 Replicon chromosome
Accession NC_013850
Organism Klebsiella variicola At-22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1893245..1893347 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1893209..1893349 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KVAR_RS08820 1888339..1890399 + 2061 WP_012967681.1 oligopeptidase B -
KVAR_RS08825 1890403..1891062 - 660 WP_008804267.1 exodeoxyribonuclease X -
KVAR_RS08830 1891141..1891371 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KVAR_RS08835 1891485..1891859 + 375 WP_012967682.1 CopC domain-containing protein YobA -
KVAR_RS08840 1891863..1892732 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
KVAR_RS08845 1892749..1893087 + 339 WP_008804271.1 YebY family protein -
- 1893209..1893349 - 141 - - Antitoxin
- 1893245..1893347 + 103 - - Toxin
KVAR_RS08850 1893425..1894510 - 1086 WP_012967683.1 phage integrase Arm DNA-binding domain-containing protein -
KVAR_RS26185 1894479..1894751 - 273 WP_012967684.1 excisionase -
KVAR_RS08855 1894927..1895124 - 198 WP_012967685.1 DNA polymerase III subunit theta -
KVAR_RS26190 1895544..1895738 - 195 WP_032425654.1 TraR/DksA family transcriptional regulator -
KVAR_RS08865 1895735..1896007 - 273 WP_012967686.1 DUF5405 family protein -
KVAR_RS08875 1896314..1896796 - 483 WP_012967688.1 siphovirus Gp157 family protein -
KVAR_RS08880 1896789..1897682 - 894 WP_012967689.1 recombinase RecT -
KVAR_RS08885 1897679..1897987 - 309 WP_012967690.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1888372..1946448 58076


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T24548 NC_013850:1893245-1893347 [Klebsiella variicola At-22]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT24548 NC_013850:c1893349-1893209 [Klebsiella variicola At-22]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References