Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2368514..2368658 | Replicon | chromosome |
| Accession | NZ_CP097423 | ||
| Organism | Klebsiella pneumoniae strain K153 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2368550..2368652 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2368514..2368658 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M8Y71_RS11395 (M8Y71_11395) | 2363644..2365704 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| M8Y71_RS11400 (M8Y71_11400) | 2365708..2366367 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| M8Y71_RS11405 (M8Y71_11405) | 2366446..2366676 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| M8Y71_RS11410 (M8Y71_11410) | 2366789..2367163 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| M8Y71_RS11415 (M8Y71_11415) | 2367167..2368036 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| M8Y71_RS11420 (M8Y71_11420) | 2368053..2368391 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2368514..2368658 | - | 145 | - | - | Antitoxin |
| - | 2368550..2368652 | + | 103 | - | - | Toxin |
| M8Y71_RS11425 (M8Y71_11425) | 2368785..2369066 | - | 282 | Protein_2213 | tyrosine-type recombinase/integrase | - |
| M8Y71_RS11430 (M8Y71_11430) | 2369143..2369622 | + | 480 | WP_032419797.1 | lysis protein | - |
| M8Y71_RS11435 (M8Y71_11435) | 2370077..2370272 | + | 196 | Protein_2215 | DNA polymerase V | - |
| M8Y71_RS11440 (M8Y71_11440) | 2370411..2371916 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| M8Y71_RS11445 (M8Y71_11445) | 2372166..2372594 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| M8Y71_RS11450 (M8Y71_11450) | 2372604..2372885 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T245430 NZ_CP097423:2368550-2368652 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT245430 NZ_CP097423:c2368658-2368514 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
