Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 5256027..5256171 | Replicon | chromosome |
| Accession | NZ_CP097419 | ||
| Organism | Klebsiella pneumoniae strain K229 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 5256033..5256135 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 5256027..5256171 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M8Y66_RS25800 (M8Y66_25800) | 5251800..5252081 | + | 282 | WP_032419786.1 | hypothetical protein | - |
| M8Y66_RS25805 (M8Y66_25805) | 5252091..5252519 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| M8Y66_RS25810 (M8Y66_25810) | 5252769..5254274 | - | 1506 | WP_020956680.1 | hypothetical protein | - |
| M8Y66_RS25815 (M8Y66_25815) | 5254413..5254608 | - | 196 | Protein_5046 | DNA polymerase V | - |
| M8Y66_RS25820 (M8Y66_25820) | 5255063..5255542 | - | 480 | WP_032419797.1 | lysis protein | - |
| M8Y66_RS25825 (M8Y66_25825) | 5255619..5255900 | + | 282 | Protein_5048 | tyrosine-type recombinase/integrase | - |
| - | 5256027..5256171 | + | 145 | - | - | Antitoxin |
| - | 5256033..5256135 | - | 103 | - | - | Toxin |
| M8Y66_RS25830 (M8Y66_25830) | 5256294..5256632 | - | 339 | WP_002911404.1 | YebY family protein | - |
| M8Y66_RS25835 (M8Y66_25835) | 5256649..5257518 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| M8Y66_RS25840 (M8Y66_25840) | 5257522..5257896 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| M8Y66_RS25845 (M8Y66_25845) | 5258009..5258239 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| M8Y66_RS25850 (M8Y66_25850) | 5258318..5258977 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| M8Y66_RS25855 (M8Y66_25855) | 5258981..5261041 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T245418 NZ_CP097419:c5256135-5256033 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT245418 NZ_CP097419:5256027-5256171 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
