Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1925853..1925998 Replicon chromosome
Accession NZ_CP097415
Organism Klebsiella pneumoniae strain K163

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1925889..1925991 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1925853..1925998 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8Y70_RS09305 1920983..1923043 + 2061 WP_004148850.1 oligopeptidase B -
M8Y70_RS09310 1923047..1923706 - 660 WP_032435029.1 exodeoxyribonuclease X -
M8Y70_RS09315 1923785..1924015 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M8Y70_RS09320 1924128..1924502 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M8Y70_RS09325 1924506..1925375 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M8Y70_RS09330 1925392..1925730 + 339 WP_002911404.1 YebY family protein -
- 1925853..1925998 - 146 - - Antitoxin
- 1925889..1925991 + 103 - - Toxin
M8Y70_RS09335 1926366..1926509 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M8Y70_RS09340 1926614..1927582 - 969 WP_004151446.1 VirK/YbjX family protein -
M8Y70_RS09345 1927739..1928392 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M8Y70_RS09350 1928389..1928580 - 192 WP_002911395.1 YebW family protein -
M8Y70_RS09355 1928678..1928917 - 240 WP_002911393.1 YebV family protein -
M8Y70_RS09360 1929033..1930466 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245395 NZ_CP097415:1925889-1925991 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245395 NZ_CP097415:c1925998-1925853 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References