Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1927434..1927579 Replicon chromosome
Accession NZ_CP097411
Organism Klebsiella pneumoniae strain K165-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1927470..1927572 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1927434..1927579 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8Y69_RS09325 1922564..1924624 + 2061 WP_004148850.1 oligopeptidase B -
M8Y69_RS09330 1924628..1925287 - 660 WP_032435029.1 exodeoxyribonuclease X -
M8Y69_RS09335 1925366..1925596 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M8Y69_RS09340 1925709..1926083 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M8Y69_RS09345 1926087..1926956 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M8Y69_RS09350 1926973..1927311 + 339 WP_002911404.1 YebY family protein -
- 1927434..1927579 - 146 - - Antitoxin
- 1927470..1927572 + 103 - - Toxin
M8Y69_RS09355 1927947..1928090 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M8Y69_RS09360 1928195..1929163 - 969 WP_004151446.1 VirK/YbjX family protein -
M8Y69_RS09365 1929320..1929973 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M8Y69_RS09370 1929970..1930161 - 192 WP_002911395.1 YebW family protein -
M8Y69_RS09375 1930259..1930498 - 240 WP_002911393.1 YebV family protein -
M8Y69_RS09380 1930614..1932047 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245379 NZ_CP097411:1927470-1927572 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245379 NZ_CP097411:c1927579-1927434 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References