Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 4051678..4052254 | Replicon | chromosome |
Accession | NZ_CP097367 | ||
Organism | Escherichia coli strain AGR6128 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | D3GXZ2 |
Locus tag | M7747_RS19755 | Protein ID | WP_001297643.1 |
Coordinates | 4051967..4052254 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A829G8Z0 |
Locus tag | M7747_RS19750 | Protein ID | WP_000063156.1 |
Coordinates | 4051678..4051980 (-) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M7747_RS19735 (4048274) | 4048274..4050424 | + | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
M7747_RS19740 (4050474) | 4050474..4050677 | + | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
M7747_RS19745 (4050688) | 4050688..4051644 | + | 957 | WP_001297640.1 | GTPase | - |
M7747_RS19750 (4051678) | 4051678..4051980 | - | 303 | WP_000063156.1 | BrnA antitoxin family protein | Antitoxin |
M7747_RS19755 (4051967) | 4051967..4052254 | - | 288 | WP_001297643.1 | BrnT family toxin | Toxin |
M7747_RS19760 (4052453) | 4052453..4053150 | - | 698 | Protein_3870 | IS1 family transposase | - |
M7747_RS19765 (4053207) | 4053207..4053302 | + | 96 | Protein_3871 | dienelactone hydrolase family protein | - |
M7747_RS19770 (4053448) | 4053448..4054680 | + | 1233 | WP_001339512.1 | multidrug efflux MFS transporter MdtM | - |
M7747_RS19775 (4054721) | 4054721..4056001 | + | 1281 | WP_001037382.1 | DUF445 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829GEV9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829G8Z0 |