Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/ElaA-DUF1778
Location 82992..83731 Replicon plasmid p4_va18651
Accession NZ_CP097346
Organism Enterobacter hormaechei subsp. xiangfangensis strain va18651

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag M5K26_RS25910 Protein ID WP_045334714.1
Coordinates 82992..83477 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag M5K26_RS25915 Protein ID WP_045334712.1
Coordinates 83465..83731 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5K26_RS25895 (79530) 79530..79970 + 441 WP_058672231.1 hypothetical protein -
M5K26_RS25900 (79973) 79973..81127 + 1155 WP_058672230.1 hypothetical protein -
M5K26_RS25905 (81403) 81403..82805 - 1403 Protein_89 ISNCY family transposase -
M5K26_RS25910 (82992) 82992..83477 - 486 WP_045334714.1 GNAT family N-acetyltransferase Toxin
M5K26_RS25915 (83465) 83465..83731 - 267 WP_045334712.1 DUF1778 domain-containing protein Antitoxin
M5K26_RS25920 (84368) 84368..85381 + 1014 WP_045334710.1 plasmid replication initiator RepA -
M5K26_RS25925 (86332) 86332..87138 + 807 WP_045334708.1 DUF4225 domain-containing protein -
M5K26_RS25930 (87113) 87113..87442 - 330 WP_045334705.1 hypothetical protein -
M5K26_RS25935 (87525) 87525..87863 - 339 WP_045334702.1 hypothetical protein -
M5K26_RS25940 (87878) 87878..88648 - 771 WP_045334699.1 TraX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..154302 154302
- flank IS/Tn - - 81403..82095 692


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(31-151)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17607.36 Da        Isoelectric Point: 10.1390

>T245255 WP_045334714.1 NZ_CP097346:c83477-82992 [Enterobacter hormaechei subsp. xiangfangensis]
VGRVTAPEPLTSSHQLTEFVSGEAVLDDWLKQRGLKNQALGSARTFVVCKTGTKQVVGFYSLATGSVNHVEATGNIRRNM
PDPIPVIILARLAVDVSFRGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEVAKSFYLHHGFKASQTQERTLFLKLP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10080.46 Da        Isoelectric Point: 4.3721

>AT245255 WP_045334712.1 NZ_CP097346:c83731-83465 [Enterobacter hormaechei subsp. xiangfangensis]
MKSDIQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVSDDAAIDKLL
ARKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References