24525

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 285201..285595 Replicon chromosome
Accession NC_013722
Organism Xanthomonas albilineans GPE PC73

Toxin (Protein)


Gene name EcnB Uniprot ID D2UAY6
Locus tag VB87_RS01720 Protein ID WP_012914817.1
Coordinates 285455..285595 (+) Length 47 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID D2UAY5
Locus tag VB87_RS01715 Protein ID WP_012914816.1
Coordinates 285201..285353 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VB87_RS01695 280997..281737 + 741 WP_012914814.1 type III pantothenate kinase -
VB87_RS16095 281747..282550 + 804 WP_012914815.1 hypothetical protein -
VB87_RS01710 283705..284097 + 393 WP_155393626.1 hypothetical protein -
VB87_RS16815 284101..284562 + 462 WP_155393627.1 hypothetical protein -
VB87_RS01715 285201..285353 + 153 WP_012914816.1 entericidin A/B family lipoprotein Antitoxin
VB87_RS01720 285455..285595 + 141 WP_012914817.1 entericidin A/B family lipoprotein Toxin
VB87_RS01725 285792..287081 + 1290 WP_012914818.1 tryptophan--tRNA ligase -
VB87_RS01730 287241..288173 + 933 WP_012914819.1 MBL fold metallo-hydrolase -
VB87_RS01735 288577..289071 - 495 WP_012914820.1 hypothetical protein -
VB87_RS01740 289625..290536 + 912 WP_045757153.1 EamA family transporter RarD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 47 a.a.        Molecular weight: 4812.64 Da        Isoelectric Point: 10.1125

>T24525 WP_012914817.1 NC_013722:285455-285595 [Xanthomonas albilineans GPE PC73]
MKRTFAWMLLAIFSAGLLSACNTVAGAGKDVQKAGEKVEDAAAKKN

Download         Length: 141 bp

>T24525 NC_013722:285455-285595 [Xanthomonas albilineans GPE PC73]
ATGAAGCGTACGTTTGCGTGGATGCTGTTGGCGATCTTCTCGGCGGGCCTGCTGTCCGCTTGTAACACCGTTGCCGGTGC
CGGCAAGGATGTGCAGAAGGCTGGCGAGAAAGTCGAAGACGCGGCTGCCAAGAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5226.19 Da        Isoelectric Point: 8.1219

>AT24525 WP_012914816.1 NC_013722:285201-285353 [Xanthomonas albilineans GPE PC73]
MKRLTTLMMLTLFCAGLLSGCNTVAGAGKDMQKAGEKVEDKAQDCSAGKC

Download         Length: 153 bp

>AT24525 NC_013722:285201-285353 [Xanthomonas albilineans GPE PC73]
ATGAAGCGACTGACTACCCTGATGATGCTGACCCTGTTCTGCGCTGGCCTGCTGAGCGGCTGCAACACTGTCGCTGGTGC
CGGCAAGGATATGCAGAAGGCCGGCGAGAAGGTGGAGGACAAGGCCCAGGATTGCAGCGCGGGCAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6P1SCH3


Antitoxin

Source ID Structure
AlphaFold DB A0A6P1SBL1

References