Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1506787..1507309 Replicon chromosome
Accession NZ_CP097335
Organism Mannheimia haemolytica strain NCTC 10208

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M3704_RS07060 Protein ID WP_154704097.1
Coordinates 1507013..1507309 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag M3704_RS07055 Protein ID WP_021279403.1
Coordinates 1506787..1507029 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3704_RS07030 (M3704_07030) 1502583..1503671 - 1089 WP_154704102.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
M3704_RS07035 (M3704_07035) 1503851..1504492 - 642 WP_154704101.1 orotate phosphoribosyltransferase -
M3704_RS07040 (M3704_07040) 1504652..1505494 - 843 WP_154704100.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
M3704_RS07045 (M3704_07045) 1505554..1506129 + 576 WP_154704099.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
M3704_RS07050 (M3704_07050) 1506107..1506775 - 669 WP_154704098.1 bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA -
M3704_RS07055 (M3704_07055) 1506787..1507029 - 243 WP_021279403.1 CopG family antitoxin Antitoxin
M3704_RS07060 (M3704_07060) 1507013..1507309 - 297 WP_154704097.1 BrnT family toxin Toxin
M3704_RS07065 (M3704_07065) 1507436..1510348 - 2913 WP_154704096.1 RNA polymerase-associated protein RapA -
M3704_RS07070 (M3704_07070) 1510509..1510868 - 360 WP_126302319.1 hypothetical protein -
M3704_RS07075 (M3704_07075) 1510931..1512256 - 1326 WP_154704095.1 anti-phage deoxyguanosine triphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(15-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11943.75 Da        Isoelectric Point: 7.9808

>T245193 WP_154704097.1 NZ_CP097335:c1507309-1507013 [Mannheimia haemolytica]
MYIDLQYAVPLLFEYDPNKSQINLAKHGIDFEQAKLLWEDERKVVLEACTEPELRYFAIGKIYDKYWTAFFTPRNDIIRL
ISVRRSRKKEISYYEKYH

Download         Length: 297 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9318.74 Da        Isoelectric Point: 7.1665

>AT245193 WP_021279403.1 NZ_CP097335:c1507029-1506787 [Mannheimia haemolytica]
MRNTISAEELERIFDEGKEDILQYCDLSTAHRPGQMKRVNVDFPNWMVEALDKQARHLGVPRQALIKMWIAEKLPAQSPR

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References