Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 2595277..2595800 Replicon chromosome
Accession NZ_CP097330
Organism Cupriavidus campinensis strain G5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M5D45_RS12255 Protein ID WP_144198090.1
Coordinates 2595277..2595537 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M5D45_RS12260 Protein ID WP_144198136.1
Coordinates 2595534..2595800 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D45_RS12240 (M5D45_12240) 2592434..2593654 + 1221 WP_144198093.1 CaiB/BaiF CoA-transferase family protein -
M5D45_RS12245 (M5D45_12245) 2593733..2594188 + 456 WP_149135466.1 DUF2214 family protein -
M5D45_RS12250 (M5D45_12250) 2594219..2595247 + 1029 WP_144198091.1 tripartite tricarboxylate transporter substrate binding protein -
M5D45_RS12255 (M5D45_12255) 2595277..2595537 - 261 WP_144198090.1 Txe/YoeB family addiction module toxin Toxin
M5D45_RS12260 (M5D45_12260) 2595534..2595800 - 267 WP_144198136.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M5D45_RS12265 (M5D45_12265) 2595889..2597661 - 1773 WP_250024701.1 potassium/proton antiporter -
M5D45_RS12270 (M5D45_12270) 2598059..2598520 + 462 WP_144198088.1 tripartite tricarboxylate transporter TctB family protein -
M5D45_RS12275 (M5D45_12275) 2598534..2600036 + 1503 WP_144198087.1 tripartite tricarboxylate transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10218.61 Da        Isoelectric Point: 8.8746

>T245172 WP_144198090.1 NZ_CP097330:c2595537-2595277 [Cupriavidus campinensis]
MTRKVLFTPDAREDYVYWQGQDRKTLKRINQLIKEVQRTPFEGIGKPEPLVGNLTGFWSRRIDDANRLVYEATEDQVNIV
ACRYHY

Download         Length: 261 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9799.89 Da        Isoelectric Point: 5.0967

>AT245172 WP_144198136.1 NZ_CP097330:c2595800-2595534 [Cupriavidus campinensis]
MRTVHFSDARNNLKAVIDQTIDDADVTLITRRDAPNAVLMSQDLYESIAETLHLLRSRANADRLASSIAQLRGGNTKERA
LHEPEGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References