Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 4283260..4283903 Replicon chromosome
Accession NZ_CP097329
Organism Pseudanabaena mucicola str. Chao 1806

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M4D78_RS20650 Protein ID WP_286393085.1
Coordinates 4283260..4283649 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M4D78_RS20655 Protein ID WP_286393087.1
Coordinates 4283658..4283903 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4D78_RS20635 4278582..4281938 + 3357 WP_286393082.1 Swt1 family HEPN domain-containing protein -
M4D78_RS20640 4282376..4282633 - 258 WP_286393083.1 glutaredoxin family protein -
M4D78_RS20650 4283260..4283649 - 390 WP_286393085.1 type II toxin-antitoxin system VapC family toxin Toxin
M4D78_RS20655 4283658..4283903 - 246 WP_286393087.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M4D78_RS20660 4283937..4284161 - 225 WP_286393089.1 putative molybdenum carrier protein -
M4D78_RS20665 4284282..4284671 - 390 WP_286393091.1 nuclease A inhibitor family protein -
M4D78_RS20670 4284806..4285156 + 351 WP_286393093.1 hypothetical protein -
M4D78_RS20675 4285295..4285711 + 417 WP_286393095.1 hypothetical protein -
M4D78_RS20680 4285776..4286144 + 369 WP_286393097.1 hypothetical protein -
M4D78_RS20685 4286196..4286465 + 270 WP_286393099.1 transposase -
M4D78_RS20695 4286778..4287791 - 1014 WP_286393100.1 ferrochelatase -
M4D78_RS20700 4288184..4288570 - 387 WP_286393102.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14671.87 Da        Isoelectric Point: 4.6461

>T245168 WP_286393085.1 NZ_CP097329:c4283649-4283260 [Pseudanabaena mucicola str. Chao 1806]
MDTHIWLWWFAQPERLSEEAIACIVDETNEVWFSVASVWEMSIKVALGKLPLPEPVDSYISSRMVQLGARSLDISVNHAL
KAAALPLHHRDPFDRMLIAQAQLENITIVTADHMFSQYQDVSILWAANL

Download         Length: 390 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8808.04 Da        Isoelectric Point: 4.7513

>AT245168 WP_286393087.1 NZ_CP097329:c4283903-4283658 [Pseudanabaena mucicola str. Chao 1806]
METVNIHQAKTNLSRLLARVELGEEIVISNRGVPVAKLVPFCTSSNRKASLGIDKGRFIVPEDFNDPLPEDILSAFEGGE
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References