Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3057005..3057507 Replicon chromosome
Accession NZ_CP097329
Organism Pseudanabaena mucicola str. Chao 1806

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M4D78_RS14790 Protein ID WP_286391580.1
Coordinates 3057253..3057507 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M4D78_RS14785 Protein ID WP_126388797.1
Coordinates 3057005..3057256 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4D78_RS14750 3052489..3053373 + 885 WP_286391562.1 MBL fold metallo-hydrolase -
M4D78_RS14755 3053540..3054667 + 1128 WP_286391565.1 type III polyketide synthase -
M4D78_RS14760 3054719..3055465 + 747 WP_286391568.1 methyltransferase domain-containing protein -
M4D78_RS14765 3055423..3055686 - 264 WP_286391570.1 hypothetical protein -
M4D78_RS14770 3055655..3055999 - 345 WP_286391572.1 hypothetical protein -
M4D78_RS14775 3056105..3056599 + 495 WP_286391574.1 restriction endonuclease -
M4D78_RS14780 3056620..3056817 - 198 WP_286391577.1 hypothetical protein -
M4D78_RS14785 3057005..3057256 + 252 WP_126388797.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M4D78_RS14790 3057253..3057507 + 255 WP_286391580.1 Txe/YoeB family addiction module toxin Toxin
M4D78_RS14795 3057516..3058676 + 1161 WP_286391583.1 NAD(P)/FAD-dependent oxidoreductase -
M4D78_RS14800 3058638..3059900 - 1263 WP_286391586.1 MFS transporter -
M4D78_RS14805 3060010..3060675 - 666 WP_286391588.1 pentapeptide repeat-containing protein -
M4D78_RS14810 3060791..3061519 + 729 WP_286391591.1 hypothetical protein -
M4D78_RS14815 3061701..3062087 + 387 WP_286391594.1 glycine cleavage system protein GcvH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10193.69 Da        Isoelectric Point: 9.5602

>T245166 WP_286391580.1 NZ_CP097329:3057253-3057507 [Pseudanabaena mucicola str. Chao 1806]
VKLIFSERAWEDYLYWQKTDKKILNRINSLIKDIQRDPYSGIGKPEALKHGLSGYWSRRIDDEHRILYKVEDNALLLVQI
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9205.35 Da        Isoelectric Point: 4.4131

>AT245166 WP_126388797.1 NZ_CP097329:3057005-3057256 [Pseudanabaena mucicola str. Chao 1806]
MNAVSYVEAQSNLAKMIDQVCDNHDPVVITRHQQPSAVLLSLEDYESLAETAYLLKSRNNAKRIFEAIAELESGGGTVRE
LIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References