Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 2699785..2700581 Replicon chromosome
Accession NZ_CP097329
Organism Pseudanabaena mucicola str. Chao 1806

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag M4D78_RS13050 Protein ID WP_286390830.1
Coordinates 2699785..2700288 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag M4D78_RS13055 Protein ID WP_286390832.1
Coordinates 2700285..2700581 (-) Length 99 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4D78_RS13010 2694904..2695164 - 261 WP_286390812.1 hypothetical protein -
M4D78_RS13015 2695161..2695391 - 231 WP_286390813.1 hypothetical protein -
M4D78_RS13020 2695409..2695537 - 129 WP_286390816.1 DUF433 domain-containing protein -
M4D78_RS13025 2695599..2695796 - 198 WP_286390819.1 hypothetical protein -
M4D78_RS13030 2695846..2697042 - 1197 WP_286390821.1 hypothetical protein -
M4D78_RS13035 2697074..2697277 - 204 WP_286390824.1 DUF2281 domain-containing protein -
M4D78_RS13040 2697292..2699172 - 1881 WP_286390826.1 N-6 DNA methylase -
M4D78_RS13045 2699206..2699676 - 471 WP_286390828.1 DUF29 domain-containing protein -
M4D78_RS13050 2699785..2700288 - 504 WP_286390830.1 GNAT family N-acetyltransferase Toxin
M4D78_RS13055 2700285..2700581 - 297 WP_286390832.1 DUF1778 domain-containing protein Antitoxin
M4D78_RS13060 2700818..2701426 + 609 WP_286390835.1 hypothetical protein -
M4D78_RS13065 2701668..2704700 - 3033 WP_286390837.1 L-glutamate gamma-semialdehyde dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(46-146)

Antitoxin

(10-98)


Sequences


Toxin        


Download         Length: 168 a.a.        Molecular weight: 18480.48 Da        Isoelectric Point: 9.1718

>T245165 WP_286390830.1 NZ_CP097329:c2700288-2699785 [Pseudanabaena mucicola str. Chao 1806]
MSLDNLRSPEKLNLSHQIKGFDSGNSQLDDWLKNRAIKNEIEGASRTYVLCNGDVVIGFYCLANGSVFQSVATGKVRRNM
PDPIPVMVIGRLAIDRSWQGKGLGRALLKDAILRTLQASEIAGIRAILVHAISENAKLFYEKCGFTVSPIDEMTLMIRIK
DAITVFQ

Download         Length: 504 bp


Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11301.71 Da        Isoelectric Point: 4.7872

>AT245165 WP_286390832.1 NZ_CP097329:c2700581-2700285 [Pseudanabaena mucicola str. Chao 1806]
MSTSIDNITSSQNRDVTINIRVKQEQRNIIDRAAEVQGKTRSEFMLESAYQKAQDVLLDWAFFDLDPSKYQEFTALLDGV
PQPNPKLQKLLTNKSPWE

Download         Length: 297 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References