Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2610634..2611291 Replicon chromosome
Accession NZ_CP097327
Organism Providencia vermicola strain P13

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag M5J11_RS11850 Protein ID WP_163860914.1
Coordinates 2610881..2611291 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag M5J11_RS11845 Protein ID WP_154624313.1
Coordinates 2610634..2610900 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5J11_RS11830 (M5J11_11830) 2605786..2608662 + 2877 WP_251463864.1 aminomethyl-transferring glycine dehydrogenase -
M5J11_RS11835 (M5J11_11835) 2608759..2609379 - 621 WP_154624315.1 HD domain-containing protein -
M5J11_RS11840 (M5J11_11840) 2609391..2610380 - 990 WP_154624314.1 tRNA-modifying protein YgfZ -
M5J11_RS11845 (M5J11_11845) 2610634..2610900 + 267 WP_154624313.1 FAD assembly factor SdhE Antitoxin
M5J11_RS11850 (M5J11_11850) 2610881..2611291 + 411 WP_163860914.1 protein YgfX Toxin
M5J11_RS11855 (M5J11_11855) 2611336..2611854 - 519 WP_154624312.1 flavodoxin FldB -
M5J11_RS11860 (M5J11_11860) 2611939..2612862 + 924 WP_154624329.1 site-specific tyrosine recombinase XerD -
M5J11_RS11865 (M5J11_11865) 2612882..2613583 + 702 WP_154624311.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
M5J11_RS11870 (M5J11_11870) 2613593..2615326 + 1734 WP_196713356.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15375.24 Da        Isoelectric Point: 10.8779

>T245159 WP_163860914.1 NZ_CP097327:2610881-2611291 [Providencia vermicola]
VVLWKSNLSISWKTQLFSTCAHGLVGFILLVAPWAPGNSMVWLPLLAIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWNIIKQPWCSRVGILLTLSALQGKQQKIRLWIAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10578.07 Da        Isoelectric Point: 4.7132

>AT245159 WP_154624313.1 NZ_CP097327:2610634-2610900 [Providencia vermicola]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLSDKDKQTFVRLLECADPDLFNWLMNHGRPDDEELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References