Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 2336996..2337522 Replicon chromosome
Accession NZ_CP097322
Organism Streptomyces sp. RerS4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M4D82_RS10720 Protein ID WP_249765827.1
Coordinates 2337268..2337522 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M4D82_RS10715 Protein ID WP_249765826.1
Coordinates 2336996..2337271 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4D82_RS10690 (M4D82_10690) 2332339..2333139 - 801 WP_249765822.1 peroxide stress protein YaaA -
M4D82_RS10695 (M4D82_10695) 2333285..2334754 + 1470 WP_249765823.1 RNB domain-containing ribonuclease -
M4D82_RS10700 (M4D82_10700) 2334762..2335595 - 834 WP_249765824.1 hypothetical protein -
M4D82_RS10705 (M4D82_10705) 2335592..2336335 - 744 WP_249765825.1 MerR family transcriptional regulator -
M4D82_RS10715 (M4D82_10715) 2336996..2337271 + 276 WP_249765826.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M4D82_RS10720 (M4D82_10720) 2337268..2337522 + 255 WP_249765827.1 Txe/YoeB family addiction module toxin Toxin
M4D82_RS10725 (M4D82_10725) 2337581..2339055 - 1475 Protein_2131 bifunctional RNase H/acid phosphatase -
M4D82_RS10730 (M4D82_10730) 2339055..2339798 - 744 WP_249771678.1 C4-type zinc ribbon domain-containing protein -
M4D82_RS10735 (M4D82_10735) 2339795..2340652 - 858 WP_249765828.1 Nif3-like dinuclear metal center hexameric protein -
M4D82_RS10740 (M4D82_10740) 2340875..2341954 + 1080 WP_249765829.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10121.55 Da        Isoelectric Point: 10.1925

>T245139 WP_249765827.1 NZ_CP097322:2337268-2337522 [Streptomyces sp. RerS4]
VKVVFSSRAWDQYTYWTTADPKILKRINRLIKEIQRTPFEGAGKPEPLKESLSGWWSRRITDEHRLVYRIRDEAVEIAQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10312.38 Da        Isoelectric Point: 4.2492

>AT245139 WP_249765826.1 NZ_CP097322:2336996-2337271 [Streptomyces sp. RerS4]
MPISANEARTRFYPLIRQVNEDHEPIEVTSREHGDVVIMSAEDFRSWQETVYLLRSPRNAQILMESIAELDAGHGQAREL
VETTDDAESAA

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References