Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 60417..60979 Replicon plasmid p.J383
Accession NZ_CP097295
Organism Vibrio sp. J383

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag M4S28_RS25815 Protein ID WP_249633856.1
Coordinates 60417..60719 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag M4S28_RS25820 Protein ID WP_249633857.1
Coordinates 60719..60979 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4S28_RS25800 (M4S28_25800) 56584..57249 - 666 WP_249633878.1 IS6 family transposase -
M4S28_RS25805 (M4S28_25805) 57500..57982 - 483 WP_132714993.1 hypothetical protein -
M4S28_RS25810 (M4S28_25810) 58692..60188 + 1497 WP_249633855.1 nuclease-related domain-containing protein -
M4S28_RS25815 (M4S28_25815) 60417..60719 - 303 WP_249633856.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M4S28_RS25820 (M4S28_25820) 60719..60979 - 261 WP_249633857.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M4S28_RS25825 (M4S28_25825) 61195..61761 + 567 WP_249633858.1 recombinase family protein -
M4S28_RS25830 (M4S28_25830) 61933..62202 + 270 WP_102340850.1 hypothetical protein -
M4S28_RS25835 (M4S28_25835) 62323..62745 - 423 WP_249633859.1 VOC family protein -
M4S28_RS25840 (M4S28_25840) 63035..63658 - 624 WP_249633860.1 DJ-1/PfpI family protein -
M4S28_RS25845 (M4S28_25845) 64034..64531 - 498 WP_058118984.1 DUF4865 family protein -
M4S28_RS25850 (M4S28_25850) 64528..64932 - 405 WP_249633861.1 tautomerase family protein -
M4S28_RS25855 (M4S28_25855) 64923..65258 - 336 WP_058118982.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..201166 201166
- flank IS/Tn - - 56584..57225 641


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-64)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11788.57 Da        Isoelectric Point: 9.8773

>T245116 WP_249633856.1 NZ_CP097295:c60719-60417 [Vibrio sp. J383]
MTHYKLSSSAQSDLIEIRRYTLERWGQAQWTTYFSELKQSMELLANNKLLGIEVSEVGQNYFRFPLKRHVIYYIQKQDHI
IITAVLGKHMSPAKHFSQLS

Download         Length: 303 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9660.06 Da        Isoelectric Point: 4.4230

>AT245116 WP_249633857.1 NZ_CP097295:c60979-60719 [Vibrio sp. J383]
MQSLTANTAKTKFGDLLMKVQREPIQINKNGSPVAVMMSFEEYEQLEALKLMVVKSRFEQAEADALSDKLVDGDDFMNAL
NQGKFD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References