Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 171282..171795 Replicon chromosome
Accession NZ_CP097294
Organism Vibrio sp. J383

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M4S28_RS17265 Protein ID WP_017069754.1
Coordinates 171529..171795 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1B1C1X1
Locus tag M4S28_RS17260 Protein ID WP_017061616.1
Coordinates 171282..171539 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4S28_RS17240 (M4S28_17240) 167317..167724 - 408 WP_102456263.1 hypothetical protein -
M4S28_RS17245 (M4S28_17245) 167918..169249 - 1332 WP_249633321.1 ferric reductase-like transmembrane domain-containing protein -
M4S28_RS17250 (M4S28_17250) 169426..170115 + 690 WP_102362668.1 flavin reductase -
M4S28_RS17255 (M4S28_17255) 170304..171095 + 792 WP_102450578.1 hypothetical protein -
M4S28_RS17260 (M4S28_17260) 171282..171539 + 258 WP_017061616.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M4S28_RS17265 (M4S28_17265) 171529..171795 + 267 WP_017069754.1 Txe/YoeB family addiction module toxin Toxin
M4S28_RS17270 (M4S28_17270) 171827..172150 + 324 WP_249633322.1 DUF4144 domain-containing protein -
M4S28_RS17275 (M4S28_17275) 172250..173578 - 1329 WP_004732879.1 anaerobic C4-dicarboxylate transporter -
M4S28_RS17280 (M4S28_17280) 173990..174649 + 660 WP_102442037.1 HAD family phosphatase -
M4S28_RS17285 (M4S28_17285) 174846..175472 + 627 WP_249633323.1 HD domain-containing protein -
M4S28_RS17290 (M4S28_17290) 175514..176041 + 528 WP_249633324.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10524.97 Da        Isoelectric Point: 9.3651

>T245114 WP_017069754.1 NZ_CP097294:171529-171795 [Vibrio sp. J383]
MTNDRKIVFTDNAWEDYLYWQTQDKKTLKKLNKLIEAAKRTPFEGIGKPEPLVGNLSGFWSRRIDDKNRLVYKADDDNFY
IIACRHHY

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9534.55 Da        Isoelectric Point: 4.1353

>AT245114 WP_017061616.1 NZ_CP097294:171282-171539 [Vibrio sp. J383]
MNIVSFTEARNSLKSVLDRVVDDSDVTVITRRDSEDAVVMSLDHFNSMQETLYLMSSPKNAERLAESIAQLEAGNTTVRE
LNNDE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1B1C1X1

References