Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2680087..2680744 Replicon chromosome
Accession NZ_CP097291
Organism Providencia sp. PROV188

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag M5X66_RS12360 Protein ID WP_036951135.1
Coordinates 2680087..2680497 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag M5X66_RS12365 Protein ID WP_036951240.1
Coordinates 2680478..2680744 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5X66_RS12340 (M5X66_12335) 2676062..2677795 - 1734 WP_036951130.1 single-stranded-DNA-specific exonuclease RecJ -
M5X66_RS12345 (M5X66_12340) 2677804..2678505 - 702 WP_036951131.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
M5X66_RS12350 (M5X66_12345) 2678523..2679425 - 903 WP_036951132.1 site-specific tyrosine recombinase XerD -
M5X66_RS12355 (M5X66_12350) 2679543..2680061 + 519 WP_036951134.1 flavodoxin FldB -
M5X66_RS12360 (M5X66_12355) 2680087..2680497 - 411 WP_036951135.1 protein YgfX Toxin
M5X66_RS12365 (M5X66_12360) 2680478..2680744 - 267 WP_036951240.1 FAD assembly factor SdhE Antitoxin
M5X66_RS12370 (M5X66_12365) 2681036..2682022 + 987 WP_270103602.1 tRNA-modifying protein YgfZ -
M5X66_RS12375 (M5X66_12370) 2682034..2682654 + 621 WP_036951137.1 HD domain-containing protein -
M5X66_RS12380 (M5X66_12375) 2682724..2685600 - 2877 WP_036951138.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15439.37 Da        Isoelectric Point: 10.7520

>T245108 WP_036951135.1 NZ_CP097291:c2680497-2680087 [Providencia sp. PROV188]
VVLWKSNLSISWKTQLFSTCLHGVTGIILLVAPWAPGNSMIWLPLLVVLVASWAKSQKNIAKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRFGILLTLNALQGKPQKLRLWIAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10720.26 Da        Isoelectric Point: 4.9148

>AT245108 WP_036951240.1 NZ_CP097291:c2680744-2680478 [Providencia sp. PROV188]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRVFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References