Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 3158134..3158720 Replicon chromosome
Accession NZ_CP097269
Organism Acidovorax sp. GBBC 1281

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag M5C96_RS14760 Protein ID WP_272563913.1
Coordinates 3158376..3158720 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag M5C96_RS14755 Protein ID WP_272563912.1
Coordinates 3158134..3158376 (+) Length 81 a.a.

Genomic Context

M5C96_RS14730M5C96_RS14735M5C96_RS14740M5C96_RS14745M5C96_RS14755M5C96_RS14760M5C96_RS14765M5C96_RS14775M5C96_RS14725M5C96_RS14750M5C96_RS14770M5C96_RS14780M5C96_RS14785
Location: 3155362..3155781 (420 bp)
Type: Others
Protein ID: WP_272563908.1
Location: 3155819..3156085 (267 bp)
Type: Others
Protein ID: WP_272563909.1
Location: 3156151..3156471 (321 bp)
Type: Others
Protein ID: WP_272563910.1
Location: 3156477..3156767 (291 bp)
Type: Others
Protein ID: WP_272563911.1
Location: 3158134..3158376 (243 bp)
Type: Antitoxin
Protein ID: WP_272563912.1
Location: 3158376..3158720 (345 bp)
Type: Toxin
Protein ID: WP_272563913.1
Location: 3159054..3159155 (102 bp)
Type: Others
Protein ID: Protein_2913
Location: 3160263..3161165 (903 bp)
Type: Others
Protein ID: Protein_2915
Location: 3154646..3155233 (588 bp)
Type: Others
Protein ID: WP_272563907.1
Location: 3156859..3157944 (1086 bp)
Type: Others
Protein ID: WP_272569564.1
Location: 3159153..3160247 (1095 bp)
Type: Others
Protein ID: WP_272563777.1
Location: 3161184..3161387 (204 bp)
Type: Others
Protein ID: WP_272563914.1
Location: 3161429..3162379 (951 bp)
Type: Others
Protein ID: WP_272563915.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M5C96_RS14725 (M5C96_14735)3154646..3155233-588WP_272563907.1hypothetical protein-
M5C96_RS14730 (M5C96_14740)3155362..3155781+420WP_272563908.1XRE family transcriptional regulator-
M5C96_RS14735 (M5C96_14745)3155819..3156085+267WP_272563909.1hypothetical protein-
M5C96_RS14740 (M5C96_14750)3156151..3156471+321WP_272563910.1hypothetical protein-
M5C96_RS14745 (M5C96_14755)3156477..3156767+291WP_272563911.1hypothetical protein-
M5C96_RS14750 (M5C96_14760)3156859..3157944-1086WP_272569564.1IS5 family transposase-
M5C96_RS14755 (M5C96_14765)3158134..3158376+243WP_272563912.1hypothetical proteinAntitoxin
M5C96_RS14760 (M5C96_14770)3158376..3158720+345WP_272563913.1type II toxin-antitoxin system PemK/MazF family toxinToxin
M5C96_RS14765 (M5C96_14775)3159054..3159155+102Protein_2913IS5/IS1182 family transposase-
M5C96_RS14770 (M5C96_14780)3159153..3160247-1095WP_272563777.1IS630 family transposase-
M5C96_RS14775 (M5C96_14785)3160263..3161165+903Protein_2915IS5 family transposase-
M5C96_RS14780 (M5C96_14790)3161184..3161387-204WP_272563914.1hypothetical protein-
M5C96_RS14785 (M5C96_14795)3161429..3162379-951WP_272563915.1IS5 family transposase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element-hsiC1/vipB / hsiB1/vipA3082494..316149679002


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-111)

Antitoxin

Antitoxin PemI-like

(1-77)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12767.57 Da        Isoelectric Point: 7.4364

>T245098 WP_272563913.1 NZ_CP097269:3158376-3158720 [Acidovorax sp. GBBC 1281]
MFIPNRGDIVHLEFDPASGKEMKGKHYALVLSSKEFNRRGLAMVCPISQGAAESARTHGTLVSLMNTGTDTQGTVHCHQL
KSLDWKERRFKHKETVPDEVMDEVNARVSAILFD

Download         Length: 345 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8623.21 Da        Isoelectric Point: 6.2568

>AT245098 WP_272563912.1 NZ_CP097269:3158134-3158376 [Acidovorax sp. GBBC 1281]
MKLSIQKWGNSAALRLPVGMLSALGAKVGDAFEVDLSAGQVLLRVAKPRYKLADLLAEMPEQLPRVEGWDAMTAVGLEVM

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References