Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 2654389..2655761 Replicon chromosome
Accession NZ_CP097269
Organism Acidovorax sp. GBBC 1281

Toxin (Protein)


Gene name avrRxo1 Uniprot ID -
Locus tag M5C96_RS12310 Protein ID WP_272569373.1
Coordinates 2654389..2655468 (+) Length 360 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID -
Locus tag M5C96_RS12315 Protein ID WP_272569374.1
Coordinates 2655465..2655761 (+) Length 99 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5C96_RS12285 (M5C96_12290) 2649716..2650528 + 813 WP_272569368.1 NAD-dependent deacylase -
M5C96_RS12290 (M5C96_12295) 2650937..2651611 + 675 WP_272569697.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
M5C96_RS12295 (M5C96_12300) 2651628..2652587 - 960 WP_272569369.1 aldo/keto reductase -
M5C96_RS12300 (M5C96_12305) 2652756..2653412 - 657 WP_272569370.1 chromate transporter -
M5C96_RS12305 (M5C96_12310) 2653409..2654017 - 609 WP_272569371.1 chromate transporter -
M5C96_RS12310 (M5C96_12315) 2654389..2655468 + 1080 WP_272569373.1 XopAJ/AvrRxo1 family type III secretion system effector zeta toxin Toxin
M5C96_RS12315 (M5C96_12320) 2655465..2655761 + 297 WP_272569374.1 hypothetical protein Antitoxin
M5C96_RS12320 (M5C96_12325) 2655825..2656670 + 846 WP_272569375.1 fumarylacetoacetate hydrolase family protein -
M5C96_RS12325 (M5C96_12330) 2656704..2658677 - 1974 WP_272569376.1 TonB-dependent receptor -
M5C96_RS12330 (M5C96_12335) 2658800..2659501 - 702 WP_272569377.1 superoxide dismutase family protein -
M5C96_RS12335 (M5C96_12340) 2659788..2660363 + 576 WP_272569378.1 retropepsin-like aspartic protease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(88-222)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 360 a.a.        Molecular weight: 38366.44 Da        Isoelectric Point: 7.1496

>T245097 WP_272569373.1 NZ_CP097269:2654389-2655468 [Acidovorax sp. GBBC 1281]
VRSAISALRSLPAWRTSHSAAFNGAYANGSVEMFTVGTLPPVGPGRWAYLADPAHWQPKRRKLHDALIDDSLRKATVFAE
CVERLGCDPTLFALRGNTAAGKTRLARSAVPALADALQESGGGSINPDAFKSRLRKAPGQPRLTPANVHAESCVLADRLE
RQIATGKTASGKPASMLVDKRLGGAHEVASYIALSENTGRQVEMYDIDMPLERSLLGVLQRDPDGDDPRPPYAAVVAGYS
AIRGNRLDVIDQFLAKPQIGTYHLMGTSATGEKAPVATVASGELTIHDADQYAEILALSDLPASDIGEQVIDDETIRQLT
QAMPAAIAVTAREALQKYAGLSWSQALGIHCTLNGQDRR

Download         Length: 1080 bp


Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11455.81 Da        Isoelectric Point: 7.0082

>AT245097 WP_272569374.1 NZ_CP097269:2655465-2655761 [Acidovorax sp. GBBC 1281]
MTQLKGEVALAFHRQLRERAQQQRTARLQDAKAQAASSGKEAFDLGKLQTLYDTTQRGRWTDLAQQAMVYEYLYYVEYSQ
VPDLRAFARSLDEIDYWS

Download         Length: 297 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References