Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1884979..1885612 Replicon chromosome
Accession NZ_CP097266
Organism Acidovorax sp. NCPPB 3859

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M5C97_RS08735 Protein ID WP_271451387.1
Coordinates 1885199..1885612 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M5C97_RS08730 Protein ID WP_271451386.1
Coordinates 1884979..1885212 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5C97_RS08705 (M5C97_08700) 1880421..1880798 + 378 WP_271453924.1 RidA family protein -
M5C97_RS08710 (M5C97_08705) 1880818..1881819 + 1002 WP_271453925.1 tripartite tricarboxylate transporter substrate binding protein -
M5C97_RS08715 (M5C97_08710) 1881988..1882710 - 723 WP_271453926.1 class I SAM-dependent methyltransferase -
M5C97_RS08720 (M5C97_08715) 1882966..1883928 - 963 WP_271453980.1 IS5 family transposase -
M5C97_RS08725 (M5C97_08720) 1884315..1884650 - 336 WP_271451385.1 hypothetical protein -
M5C97_RS08730 (M5C97_08725) 1884979..1885212 + 234 WP_271451386.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M5C97_RS08735 (M5C97_08730) 1885199..1885612 + 414 WP_271451387.1 PIN domain-containing protein Toxin
M5C97_RS08740 (M5C97_08735) 1885633..1885995 + 363 WP_271451388.1 DUF3742 family protein -
M5C97_RS08745 (M5C97_08740) 1886006..1887526 - 1521 Protein_1732 conjugal transfer protein TraG N-terminal domain-containing protein -
M5C97_RS08750 (M5C97_08745) 1887681..1889333 - 1653 WP_271451389.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1882966..1883928 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-119)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15153.49 Da        Isoelectric Point: 6.3220

>T245096 WP_271451387.1 NZ_CP097266:1885199-1885612 [Acidovorax sp. NCPPB 3859]
MAADKGKVFLDSNVVLYLLSENAAKADSAEALLQRRPVISVQVLNEVTHVCVRKLKMGWSEVGQFLALVRGFCSIVPLTV
EVHDRARQLAERHQLSFYDACIVAAAAAEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Download         Length: 414 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8637.97 Da        Isoelectric Point: 10.1756

>AT245096 WP_271451386.1 NZ_CP097266:1884979-1885212 [Acidovorax sp. NCPPB 3859]
MQVAKWGNSLAVRLPTSLVEALELREGDDIEIVVDAPRLFAVRKKPGAEAMLERLRTFRGKLPADFKFNRDEANGRG

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References