Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1885086..1885719 Replicon chromosome
Accession NZ_CP097265
Organism Acidovorax sp. GBBC 712

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M5C94_RS08730 Protein ID WP_271451387.1
Coordinates 1885306..1885719 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M5C94_RS08725 Protein ID WP_271451386.1
Coordinates 1885086..1885319 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5C94_RS08700 (M5C94_08695) 1880528..1880905 + 378 WP_271453924.1 RidA family protein -
M5C94_RS08705 (M5C94_08700) 1880925..1881926 + 1002 WP_271453925.1 tripartite tricarboxylate transporter substrate binding protein -
M5C94_RS08710 (M5C94_08705) 1882095..1882817 - 723 WP_271453926.1 class I SAM-dependent methyltransferase -
M5C94_RS08715 (M5C94_08710) 1883073..1884035 - 963 WP_271453980.1 IS5 family transposase -
M5C94_RS08720 (M5C94_08715) 1884422..1884757 - 336 WP_271451385.1 hypothetical protein -
M5C94_RS08725 (M5C94_08720) 1885086..1885319 + 234 WP_271451386.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M5C94_RS08730 (M5C94_08725) 1885306..1885719 + 414 WP_271451387.1 PIN domain-containing protein Toxin
M5C94_RS08735 (M5C94_08730) 1885740..1886102 + 363 WP_271451388.1 DUF3742 family protein -
M5C94_RS08740 (M5C94_08735) 1886113..1887633 - 1521 Protein_1731 conjugal transfer protein TraG N-terminal domain-containing protein -
M5C94_RS08745 (M5C94_08740) 1887788..1889440 - 1653 WP_271451389.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1883073..1884035 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-119)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15153.49 Da        Isoelectric Point: 6.3220

>T245095 WP_271451387.1 NZ_CP097265:1885306-1885719 [Acidovorax sp. GBBC 712]
MAADKGKVFLDSNVVLYLLSENAAKADSAEALLQRRPVISVQVLNEVTHVCVRKLKMGWSEVGQFLALVRGFCSIVPLTV
EVHDRARQLAERHQLSFYDACIVAAAAAEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Download         Length: 414 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8637.97 Da        Isoelectric Point: 10.1756

>AT245095 WP_271451386.1 NZ_CP097265:1885086-1885319 [Acidovorax sp. GBBC 712]
MQVAKWGNSLAVRLPTSLVEALELREGDDIEIVVDAPRLFAVRKKPGAEAMLERLRTFRGKLPADFKFNRDEANGRG

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References