Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 8963459..8964108 Replicon chromosome
Accession NZ_CP097263
Organism Kutzneria chonburiensis strain SMC256

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M3Q35_RS41625 Protein ID WP_273938082.1
Coordinates 8963459..8963848 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M3Q35_RS41630 Protein ID WP_273938083.1
Coordinates 8963845..8964108 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3Q35_RS41600 8958843..8959355 + 513 WP_273938076.1 DUF2231 domain-containing protein -
M3Q35_RS41605 8959391..8959828 + 438 WP_273938078.1 hypothetical protein -
M3Q35_RS41610 8960015..8960767 + 753 WP_273938079.1 alpha/beta fold hydrolase -
M3Q35_RS41615 8960764..8962794 - 2031 WP_273938080.1 ATP-dependent DNA helicase -
M3Q35_RS41620 8962827..8963453 - 627 WP_273938081.1 lipoyl(octanoyl) transferase LipB -
M3Q35_RS41625 8963459..8963848 - 390 WP_273938082.1 type II toxin-antitoxin system VapC family toxin Toxin
M3Q35_RS41630 8963845..8964108 - 264 WP_273938083.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M3Q35_RS41635 8964142..8964729 - 588 WP_273938084.1 biotin transporter BioY -
M3Q35_RS41640 8964801..8965430 - 630 WP_273944675.1 glycosyltransferase -
M3Q35_RS41645 8965433..8965825 - 393 WP_273938085.1 hypothetical protein -
M3Q35_RS41650 8966120..8967283 + 1164 WP_273938086.1 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) -
M3Q35_RS41655 8967385..8968032 + 648 WP_273938087.1 choice-of-anchor P family protein -
M3Q35_RS41660 8968063..8968632 - 570 WP_273938088.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13992.87 Da        Isoelectric Point: 4.8948

>T245094 WP_273938082.1 NZ_CP097263:c8963848-8963459 [Kutzneria chonburiensis]
VSPRTVLADTSFFIAVETGRPLRADIPQRYQVSTITIGELRAGVLTAGDERSRAARLRTLTKALETEPIPVDDQVAVAWA
ELRSDLRAAGRRMPVNDSWIAATAIAHGLPVVTQDDDYDGTPGLEVIKL

Download         Length: 390 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9964.22 Da        Isoelectric Point: 4.5822

>AT245094 WP_273938083.1 NZ_CP097263:c8964108-8963845 [Kutzneria chonburiensis]
MDEIALRELRNHTSEVLHRVEAGEELTVTVSGRPVARLVPLPRRRPYLTLSEIVANRADAGLYDELREMLPETTDDLDDP
WEKAARQ

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References