Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 8337349..8337881 Replicon chromosome
Accession NZ_CP097263
Organism Kutzneria chonburiensis strain SMC256

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M3Q35_RS38880 Protein ID WP_273937553.1
Coordinates 8337609..8337881 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M3Q35_RS38875 Protein ID WP_273944641.1
Coordinates 8337349..8337612 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3Q35_RS38840 8332464..8333645 - 1182 WP_273937548.1 4-hydroxyphenylpyruvate dioxygenase -
M3Q35_RS38845 8333801..8334271 + 471 WP_273944639.1 Lrp/AsnC family transcriptional regulator -
M3Q35_RS38850 8334310..8334810 - 501 WP_273937549.1 transcription elongation factor GreA -
M3Q35_RS38855 8335022..8335447 - 426 WP_273937550.1 DUF4307 domain-containing protein -
M3Q35_RS38860 8335568..8336449 + 882 WP_273937551.1 mycothiol conjugate amidase Mca -
M3Q35_RS38865 8336467..8336688 + 222 WP_273944640.1 hypothetical protein -
M3Q35_RS38870 8336689..8337297 + 609 WP_273937552.1 DUF1964 domain-containing protein -
M3Q35_RS38875 8337349..8337612 + 264 WP_273944641.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M3Q35_RS38880 8337609..8337881 + 273 WP_273937553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3Q35_RS38885 8337980..8338327 + 348 WP_273937554.1 hypothetical protein -
M3Q35_RS38890 8338306..8339061 - 756 WP_273937555.1 nucleotidyltransferase domain-containing protein -
M3Q35_RS38895 8339058..8339729 - 672 WP_273937556.1 nucleotidyltransferase domain-containing protein -
M3Q35_RS38900 8339730..8342210 - 2481 WP_273937557.1 polynucleotide kinase-phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10073.72 Da        Isoelectric Point: 10.1638

>T245093 WP_273937553.1 NZ_CP097263:8337609-8337881 [Kutzneria chonburiensis]
VSETPYRVVVAPGVRRTLQRLPEKIAAACVEFIVGPLAENPQRLGKPLIGPLEGCPSARRGAYRVVYRISEPERRIDVLR
VDHRADVHHV

Download         Length: 273 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9211.15 Da        Isoelectric Point: 4.0146

>AT245093 WP_273944641.1 NZ_CP097263:8337349-8337612 [Kutzneria chonburiensis]
MPLGDARDHLSEVVSEVQRTHDRVTITRHGHPAAVILAPEDLEGLEETIAILSTPGALLEIQTAQADIDAGDSVSGDDLA
AEFLGDR

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References