Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 5294539..5295104 Replicon chromosome
Accession NZ_CP097263
Organism Kutzneria chonburiensis strain SMC256

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M3Q35_RS23855 Protein ID WP_273934503.1
Coordinates 5294539..5294814 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M3Q35_RS23860 Protein ID WP_273934505.1
Coordinates 5294811..5295104 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3Q35_RS23840 5289815..5291059 + 1245 WP_273934500.1 ribonuclease D -
M3Q35_RS23845 5291200..5292390 + 1191 WP_273944433.1 thiolase family protein -
M3Q35_RS23850 5292387..5294492 + 2106 WP_273934501.1 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein -
M3Q35_RS23855 5294539..5294814 - 276 WP_273934503.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3Q35_RS23860 5294811..5295104 - 294 WP_273934505.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M3Q35_RS23865 5295184..5295699 - 516 WP_273934508.1 hypothetical protein -
M3Q35_RS23870 5295757..5296176 + 420 WP_273934510.1 MarR family transcriptional regulator -
M3Q35_RS23875 5296214..5296936 + 723 WP_273934514.1 DUF72 domain-containing protein -
M3Q35_RS23880 5296963..5297757 + 795 WP_273944435.1 DUF72 domain-containing protein -
M3Q35_RS23885 5297805..5298494 - 690 WP_273934516.1 hypothetical protein -
M3Q35_RS23890 5298664..5299023 + 360 WP_273934518.1 peptidase inhibitor family I36 protein -
M3Q35_RS23895 5299043..5299984 + 942 WP_273934520.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(36-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10696.09 Da        Isoelectric Point: 9.2989

>T245091 WP_273934503.1 NZ_CP097263:c5294814-5294539 [Kutzneria chonburiensis]
MSESYDIAWSPQARRAMAEQVPVHVAMAVYELVTGPLATNPHRIGKQLDPPMDDQWSARRGDYRVLYRIHEDKHQVYVTR
ISHRRDAYRAY

Download         Length: 276 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10660.92 Da        Isoelectric Point: 4.1190

>AT245091 WP_273934505.1 NZ_CP097263:c5295104-5294811 [Kutzneria chonburiensis]
METMPITEVKARLAELVVQVETQRDRITITRNGKPAAILVSVGEWESINETLDVLADPEALRDIKESDDAYARGEVYDSS
EIAAILRARTDGTDSVA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References