Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 825032..825692 Replicon chromosome
Accession NZ_CP097262
Organism Salmonella enterica subsp. enterica strain B3-6

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag M3N94_RS03960 Protein ID WP_000244756.1
Coordinates 825279..825692 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag M3N94_RS03955 Protein ID WP_000351186.1
Coordinates 825032..825298 (+) Length 89 a.a.

Genomic Context

M3N94_RS03940M3N94_RS03945M3N94_RS03955M3N94_RS03960M3N94_RS03970M3N94_RS03975M3N94_RS03980M3N94_RS03935M3N94_RS03950M3N94_RS03965
Location: 822552..822863 (312 bp)
Type: Others
Protein ID: WP_001182976.1
Location: 823027..823686 (660 bp)
Type: Others
Protein ID: WP_000250289.1
Location: 825032..825298 (267 bp)
Type: Antitoxin
Protein ID: WP_000351186.1
Location: 825279..825692 (414 bp)
Type: Toxin
Protein ID: WP_000244756.1
Location: 826379..827275 (897 bp)
Type: Others
Protein ID: WP_000434302.1
Location: 827299..828012 (714 bp)
Type: Others
Protein ID: WP_000745614.1
Location: 828018..829751 (1734 bp)
Type: Others
Protein ID: WP_000813389.1
Location: 820961..822394 (1434 bp)
Type: Others
Protein ID: WP_001230141.1
Location: 823802..824782 (981 bp)
Type: Others
Protein ID: WP_000874176.1
Location: 825745..826266 (522 bp)
Type: Others
Protein ID: WP_001055885.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M3N94_RS03935 (820961)820961..822394-1434WP_001230141.16-phospho-beta-glucosidase BglA-
M3N94_RS03940 (822552)822552..822863+312WP_001182976.1N(4)-acetylcytidine aminohydrolase-
M3N94_RS03945 (823027)823027..823686+660WP_000250289.1hemolysin III family protein-
M3N94_RS03950 (823802)823802..824782-981WP_000874176.1tRNA-modifying protein YgfZ-
M3N94_RS03955 (825032)825032..825298+267WP_000351186.1FAD assembly factor SdhEAntitoxin
M3N94_RS03960 (825279)825279..825692+414WP_000244756.1protein YgfXToxin
M3N94_RS03965 (825745)825745..826266-522WP_001055885.1flavodoxin FldB-
M3N94_RS03970 (826379)826379..827275+897WP_000434302.1site-specific tyrosine recombinase XerD-
M3N94_RS03975 (827299)827299..828012+714WP_000745614.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
M3N94_RS03980 (828018)828018..829751+1734WP_000813389.1single-stranded-DNA-specific exonuclease RecJ-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T245074 WP_000244756.1 NZ_CP097262:825279-825692 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT245074 WP_000351186.1 NZ_CP097262:825032-825298 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3Z1E9V5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5I0YWH4

References