Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type III Classification (family/domain) toxIN/ToxN(toxin)
Location 63242..63971 Replicon plasmid pb
Accession NZ_CP097259
Organism Bacillus thuringiensis strain Bt Gxmzu777-1

Toxin (Protein)


Gene name toxN Uniprot ID -
Locus tag M3Y14_RS32530 Protein ID WP_264541550.1
Coordinates 63242..63814 (-) Length 191 a.a.

Antitoxin (RNA)


Gene name toxI
Locus tag -
Coordinates 63877..63971 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3Y14_RS32515 (58698) 58698..60842 - 2145 WP_264541547.1 type IA DNA topoisomerase -
M3Y14_RS32520 (61009) 61009..62244 - 1236 WP_264541548.1 hypothetical protein -
M3Y14_RS32525 (62524) 62524..63168 - 645 WP_264541549.1 hypothetical protein -
M3Y14_RS32530 (63242) 63242..63814 - 573 WP_264541550.1 type III toxin-antitoxin system ToxN/AbiQ family toxin Toxin
- (63877) 63877..63971 - 95 NuclAT_0 - Antitoxin
- (63877) 63877..63971 - 95 NuclAT_0 - Antitoxin
- (63877) 63877..63971 - 95 NuclAT_0 - Antitoxin
- (63877) 63877..63971 - 95 NuclAT_0 - Antitoxin
M3Y14_RS32535 (64049) 64049..65071 - 1023 WP_264541551.1 DUF3991 and TOPRIM domain-containing protein -
M3Y14_RS32540 (65158) 65158..65709 - 552 WP_264541552.1 metal-dependent hydrolase -
M3Y14_RS32545 (65731) 65731..66717 - 987 WP_264541553.1 hypothetical protein -
M3Y14_RS32550 (66780) 66780..68411 - 1632 WP_264541554.1 ArdC-like ssDNA-binding domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..180160 180160


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-171)


Sequences


Toxin        


Download         Length: 191 a.a.        Molecular weight: 22390.81 Da        Isoelectric Point: 9.7249

>T245067 WP_264541550.1 NZ_CP097259:c63814-63242 [Bacillus thuringiensis]
MANKDNPKFYTISTKYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNLNSQVSVKLFDIDNPEKR
IGVLLVNNMIPVPEKECKEIDIAEKKETDPKYGNLMLKQYLFLKENMDRVSNKVEKVYKDVTVKGKPSHKQKFLKGVCCD
FSKLEEKCQKYKEKDQARRIAYMRQVGRER

Download         Length: 573 bp


Antitoxin


Download         Length: 95 bp

>AT245067 NZ_CP097259:c63971-63877 [Bacillus thuringiensis]
GTAGCCTTACTTTAGTAGGCGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCACAAAAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References