Detailed information of TA system
Overview
TA module
| Type | III | Classification (family/domain) | toxIN/ToxN(toxin) |
| Location | 63242..63971 | Replicon | plasmid pb |
| Accession | NZ_CP097259 | ||
| Organism | Bacillus thuringiensis strain Bt Gxmzu777-1 | ||
Toxin (Protein)
| Gene name | toxN | Uniprot ID | - |
| Locus tag | M3Y14_RS32530 | Protein ID | WP_264541550.1 |
| Coordinates | 63242..63814 (-) | Length | 191 a.a. |
Antitoxin (RNA)
| Gene name | toxI | ||
| Locus tag | - | ||
| Coordinates | 63877..63971 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M3Y14_RS32515 (58698) | 58698..60842 | - | 2145 | WP_264541547.1 | type IA DNA topoisomerase | - |
| M3Y14_RS32520 (61009) | 61009..62244 | - | 1236 | WP_264541548.1 | hypothetical protein | - |
| M3Y14_RS32525 (62524) | 62524..63168 | - | 645 | WP_264541549.1 | hypothetical protein | - |
| M3Y14_RS32530 (63242) | 63242..63814 | - | 573 | WP_264541550.1 | type III toxin-antitoxin system ToxN/AbiQ family toxin | Toxin |
| - (63877) | 63877..63971 | - | 95 | NuclAT_0 | - | Antitoxin |
| - (63877) | 63877..63971 | - | 95 | NuclAT_0 | - | Antitoxin |
| - (63877) | 63877..63971 | - | 95 | NuclAT_0 | - | Antitoxin |
| - (63877) | 63877..63971 | - | 95 | NuclAT_0 | - | Antitoxin |
| M3Y14_RS32535 (64049) | 64049..65071 | - | 1023 | WP_264541551.1 | DUF3991 and TOPRIM domain-containing protein | - |
| M3Y14_RS32540 (65158) | 65158..65709 | - | 552 | WP_264541552.1 | metal-dependent hydrolase | - |
| M3Y14_RS32545 (65731) | 65731..66717 | - | 987 | WP_264541553.1 | hypothetical protein | - |
| M3Y14_RS32550 (66780) | 66780..68411 | - | 1632 | WP_264541554.1 | ArdC-like ssDNA-binding domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..180160 | 180160 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 22390.81 Da Isoelectric Point: 9.7249
>T245067 WP_264541550.1 NZ_CP097259:c63814-63242 [Bacillus thuringiensis]
MANKDNPKFYTISTKYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNLNSQVSVKLFDIDNPEKR
IGVLLVNNMIPVPEKECKEIDIAEKKETDPKYGNLMLKQYLFLKENMDRVSNKVEKVYKDVTVKGKPSHKQKFLKGVCCD
FSKLEEKCQKYKEKDQARRIAYMRQVGRER
MANKDNPKFYTISTKYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNLNSQVSVKLFDIDNPEKR
IGVLLVNNMIPVPEKECKEIDIAEKKETDPKYGNLMLKQYLFLKENMDRVSNKVEKVYKDVTVKGKPSHKQKFLKGVCCD
FSKLEEKCQKYKEKDQARRIAYMRQVGRER
Download Length: 573 bp
Antitoxin
Download Length: 95 bp
>AT245067 NZ_CP097259:c63971-63877 [Bacillus thuringiensis]
GTAGCCTTACTTTAGTAGGCGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCACAAAAA
GTAGCCTTACTTTAGTAGGCGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCACAAAAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|