Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 5855898..5856429 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name yafQ Uniprot ID X6CWI9
Locus tag M5D98_RS28595 Protein ID WP_023764622.1
Coordinates 5856157..5856429 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID X6DV70
Locus tag M5D98_RS28590 Protein ID WP_023764621.1
Coordinates 5855898..5856155 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS28580 (M5D98_28580) 5852709..5853674 + 966 WP_224687519.1 sugar-binding transcriptional regulator -
M5D98_RS28585 (M5D98_28585) 5853758..5855812 + 2055 WP_224687518.1 bifunctional aldolase/short-chain dehydrogenase -
M5D98_RS28590 (M5D98_28590) 5855898..5856155 + 258 WP_023764621.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M5D98_RS28595 (M5D98_28595) 5856157..5856429 + 273 WP_023764622.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
M5D98_RS28600 (M5D98_28600) 5856512..5857564 - 1053 WP_023764623.1 substrate-binding domain-containing protein -
M5D98_RS28605 (M5D98_28605) 5857613..5858608 - 996 WP_224687517.1 ABC transporter permease -
M5D98_RS28610 (M5D98_28610) 5858691..5860202 - 1512 WP_224687516.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10500.10 Da        Isoelectric Point: 9.5341

>T245047 WP_023764622.1 NZ_CP097252:5856157-5856429 [Mesorhizobium opportunistum]
MLTPVRSGQFRRDVKRMEKRGKDLAKLRELLALLVAGQELPAIYKDHPLKGDWKGYRDAHVEPDWLLIYRIADDELRLAR
TGSHSDLFNE

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9149.60 Da        Isoelectric Point: 8.7135

>AT245047 WP_023764621.1 NZ_CP097252:5855898-5856155 [Mesorhizobium opportunistum]
MATDTVVRARIDTATKDQATEALAAMGLSVSDAIRLLLVRVAADKEFPFPVKVPNATTRKAMAELEKGKGERFASANELF
KDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB X6CWI9

Antitoxin

Source ID Structure
AlphaFold DB X6DV70

References