245046

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 5404570..5405041 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M5D98_RS26430 Protein ID WP_224685051.1
Coordinates 5404570..5404836 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag M5D98_RS26435 Protein ID WP_031258550.1
Coordinates 5404820..5405041 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS26400 (M5D98_26400) 5399678..5400568 - 891 WP_224685055.1 YicC/YloC family endoribonuclease -
M5D98_RS26405 (M5D98_26405) 5400715..5401797 - 1083 WP_224685054.1 endolytic transglycosylase MltG -
M5D98_RS26410 (M5D98_26410) 5401796..5402068 + 273 WP_224685053.1 hypothetical protein -
M5D98_RS26415 (M5D98_26415) 5402056..5403318 - 1263 WP_013896299.1 beta-ketoacyl-ACP synthase II -
M5D98_RS26420 (M5D98_26420) 5403353..5403589 - 237 WP_006203723.1 acyl carrier protein -
M5D98_RS26425 (M5D98_26425) 5403801..5404538 - 738 WP_224685052.1 3-oxoacyl-[acyl-carrier-protein] reductase -
M5D98_RS26430 (M5D98_26430) 5404570..5404836 - 267 WP_224685051.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M5D98_RS26435 (M5D98_26435) 5404820..5405041 - 222 WP_031258550.1 ribbon-helix-helix protein, CopG family Antitoxin
M5D98_RS26440 (M5D98_26440) 5405097..5406035 - 939 WP_224685050.1 ACP S-malonyltransferase -
M5D98_RS26445 (M5D98_26445) 5406313..5408241 + 1929 WP_224685049.1 LTA synthase family protein -
M5D98_RS26450 (M5D98_26450) 5408709..5409200 + 492 WP_224685048.1 30S ribosomal protein S6 -
M5D98_RS26455 (M5D98_26455) 5409200..5409448 + 249 WP_006203718.1 30S ribosomal protein S18 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10293.99 Da        Isoelectric Point: 10.1413

>T245046 WP_224685051.1 NZ_CP097252:c5404836-5404570 [Mesorhizobium opportunistum]
VAWTLEYPRSARKFVEKLDPKTRHRIRDFIENRIAVLDNPCEAGKALKGPLATLWRYRVGDYRIICDVQDSRLVVLVVTI
GHRADIYR

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8682.81 Da        Isoelectric Point: 4.4777

>AT245046 WP_031258550.1 NZ_CP097252:c5405041-5404820 [Mesorhizobium opportunistum]
MPTSIRLAPEIEERLDFLAARTGRSKAYYLRELIERGIEEMEDYYLAAEVRERIRRGEEDVMKGEDFWRGLDA

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References