Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | slvAT/RES(toxin) |
| Location | 4576374..4577281 | Replicon | chromosome |
| Accession | NZ_CP097252 | ||
| Organism | Mesorhizobium opportunistum strain WSM1558 | ||
Toxin (Protein)
| Gene name | slvT | Uniprot ID | - |
| Locus tag | M5D98_RS22100 | Protein ID | WP_224685740.1 |
| Coordinates | 4576374..4576898 (-) | Length | 175 a.a. |
Antitoxin (Protein)
| Gene name | slvA | Uniprot ID | - |
| Locus tag | M5D98_RS22105 | Protein ID | WP_224685739.1 |
| Coordinates | 4576895..4577281 (-) | Length | 129 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5D98_RS22080 (M5D98_22080) | 4571865..4573070 | + | 1206 | WP_224685744.1 | MFS transporter | - |
| M5D98_RS22085 (M5D98_22085) | 4573072..4574472 | + | 1401 | WP_224685743.1 | hypothetical protein | - |
| M5D98_RS22090 (M5D98_22090) | 4574657..4575610 | + | 954 | WP_224685742.1 | DUF1403 family protein | - |
| M5D98_RS22095 (M5D98_22095) | 4575613..4576335 | + | 723 | WP_224685741.1 | SMC-Scp complex subunit ScpB | - |
| M5D98_RS22100 (M5D98_22100) | 4576374..4576898 | - | 525 | WP_224685740.1 | RES family NAD+ phosphorylase | Toxin |
| M5D98_RS22105 (M5D98_22105) | 4576895..4577281 | - | 387 | WP_224685739.1 | hypothetical protein | Antitoxin |
| M5D98_RS22110 (M5D98_22110) | 4578239..4578478 | + | 240 | WP_224685738.1 | hypothetical protein | - |
| M5D98_RS22115 (M5D98_22115) | 4578828..4579226 | + | 399 | WP_224685737.1 | MAPEG family protein | - |
| M5D98_RS22120 (M5D98_22120) | 4579395..4579751 | + | 357 | WP_224685736.1 | VOC family protein | - |
| M5D98_RS22125 (M5D98_22125) | 4580052..4580519 | + | 468 | WP_224685735.1 | class I SAM-dependent methyltransferase | - |
| M5D98_RS22130 (M5D98_22130) | 4580766..4581986 | - | 1221 | WP_224685734.1 | arabinose transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 4548589..4646283 | 97694 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 175 a.a. Molecular weight: 19107.67 Da Isoelectric Point: 5.9851
>T245043 WP_224685740.1 NZ_CP097252:c4576898-4576374 [Mesorhizobium opportunistum]
VKVTRVGPDEIFHRYLTPKWAFLPTSGAGAAIDGGRFNRPGVEALYLSRSTQTALDEYKQGASIVPPATLAAYKITLAEV
ADLSQGFDPEILDSAWQEWDCAWRQIARIDKKIPPSWKLADLIITAGLRGILFPSLRHAGGTNLVIFPANLVDGDHVAVH
DPDDRLPHDQSSWP
VKVTRVGPDEIFHRYLTPKWAFLPTSGAGAAIDGGRFNRPGVEALYLSRSTQTALDEYKQGASIVPPATLAAYKITLAEV
ADLSQGFDPEILDSAWQEWDCAWRQIARIDKKIPPSWKLADLIITAGLRGILFPSLRHAGGTNLVIFPANLVDGDHVAVH
DPDDRLPHDQSSWP
Download Length: 525 bp
Antitoxin
Download Length: 129 a.a. Molecular weight: 14084.97 Da Isoelectric Point: 8.5217
>AT245043 WP_224685739.1 NZ_CP097252:c4577281-4576895 [Mesorhizobium opportunistum]
MAHAQLAHSTVISGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
SDVDKAIYWYRNEPIADYGHRTAAELVADGQVEAVLAFIRDLENGARG
MAHAQLAHSTVISGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
SDVDKAIYWYRNEPIADYGHRTAAELVADGQVEAVLAFIRDLENGARG
Download Length: 387 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|