Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3465310..3465971 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name vapC Uniprot ID X6DT42
Locus tag M5D98_RS16835 Protein ID WP_023777979.1
Coordinates 3465534..3465971 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M5D98_RS16830 Protein ID WP_224686186.1
Coordinates 3465310..3465537 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS16815 (M5D98_16815) 3460697..3461731 + 1035 WP_013894591.1 ABC transporter permease -
M5D98_RS16820 (M5D98_16820) 3461743..3462900 + 1158 WP_023765202.1 ABC transporter permease -
M5D98_RS16825 (M5D98_16825) 3462951..3465155 + 2205 WP_224686187.1 ABC transporter ATP-binding protein -
M5D98_RS16830 (M5D98_16830) 3465310..3465537 + 228 WP_224686186.1 CopG family transcriptional regulator Antitoxin
M5D98_RS16835 (M5D98_16835) 3465534..3465971 + 438 WP_023777979.1 DNA-binding protein Toxin
M5D98_RS16840 (M5D98_16840) 3466060..3466650 - 591 WP_224686185.1 transglycosylase SLT domain-containing protein -
M5D98_RS16845 (M5D98_16845) 3466867..3468405 + 1539 WP_224686184.1 trimethylamine methyltransferase family protein -
M5D98_RS16850 (M5D98_16850) 3468484..3470910 + 2427 WP_224686183.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15515.73 Da        Isoelectric Point: 7.5194

>T245042 WP_023777979.1 NZ_CP097252:3465534-3465971 [Mesorhizobium opportunistum]
VTFLFDVNVLIALIDPAHVAHEDAHRWFQSTGHLSWATCPITENGVIRILSNPKYPNSPGSPAVVAQIVGKLHALSGHQF
WSDDISLVGSSDIDAARILTSAQVTDSYLLGLAKARGGKLATFDRKLSTAAVRGGKPILHLIPSE

Download         Length: 438 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8143.23 Da        Isoelectric Point: 5.0176

>AT245042 WP_224686186.1 NZ_CP097252:3465310-3465537 [Mesorhizobium opportunistum]
VRTTLAIDDDVLLAAKAIARQQDRSIGEVISDLARHSLRRPQAGGERNGIPLLSSRSDGPIVDLEMVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB X6DT42

Antitoxin

Source ID Structure

References