245040

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3146239..3147020 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag M5D98_RS15240 Protein ID WP_224690369.1
Coordinates 3146239..3146733 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag M5D98_RS15245 Protein ID WP_224690367.1
Coordinates 3146730..3147020 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS15215 (M5D98_15215) 3141520..3142308 - 789 WP_023766160.1 ABC transporter substrate-binding protein -
M5D98_RS15220 (M5D98_15220) 3142420..3143580 - 1161 WP_224690374.1 saccharopine dehydrogenase family protein -
M5D98_RS15225 (M5D98_15225) 3143577..3144077 - 501 WP_013894264.1 Lrp/AsnC family transcriptional regulator -
M5D98_RS15230 (M5D98_15230) 3144240..3145112 - 873 WP_224690373.1 LysR substrate-binding domain-containing protein -
M5D98_RS15235 (M5D98_15235) 3145462..3146211 + 750 WP_224690370.1 sulfite exporter TauE/SafE family protein -
M5D98_RS15240 (M5D98_15240) 3146239..3146733 - 495 WP_224690369.1 GNAT family N-acetyltransferase Toxin
M5D98_RS15245 (M5D98_15245) 3146730..3147020 - 291 WP_224690367.1 DUF1778 domain-containing protein Antitoxin
M5D98_RS15250 (M5D98_15250) 3147119..3147568 - 450 WP_224690366.1 universal stress protein -
M5D98_RS15255 (M5D98_15255) 3147834..3148415 + 582 WP_224690365.1 histidine phosphatase family protein -
M5D98_RS15260 (M5D98_15260) 3148692..3149093 - 402 WP_224690364.1 VOC family protein -
M5D98_RS15265 (M5D98_15265) 3149191..3150234 - 1044 WP_224690363.1 sigma-70 family RNA polymerase sigma factor -
M5D98_RS15270 (M5D98_15270) 3150292..3151038 - 747 WP_224690362.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17378.96 Da        Isoelectric Point: 8.0963

>T245040 WP_224690369.1 NZ_CP097252:c3146733-3146239 [Mesorhizobium opportunistum]
VSLSAPVPLADHHDLNDFSSGIPSLDDWLKKRARANQAGGASRTYVTCIGNRVVGYYAIASGGVRMVETPGRFRRNMPDP
IPVVVLGRLAVDQSHHGQGIGRALVRDAGLRILQAAEILGIRGILVHAISDDARAFYMAVGFEPSPVEPLTLMATLADLG
ASLG

Download         Length: 495 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10741.33 Da        Isoelectric Point: 10.4449

>AT245040 WP_224690367.1 NZ_CP097252:c3147020-3146730 [Mesorhizobium opportunistum]
MSASQHSLPKSVPLNIRVKPEVRNLIDRAAQLLGKNRTDFMLEASQRAAEDALLNRLVFTAEPDAYAAFLARLDMSPHPN
DRLRRTMATKAPWDAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References