245039

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PrpT-parD/ParE-RHH
Location 2730888..2731414 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name PrpT Uniprot ID F7YH10
Locus tag M5D98_RS13215 Protein ID WP_013893673.1
Coordinates 2730888..2731181 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag M5D98_RS13220 Protein ID WP_224688184.1
Coordinates 2731178..2731414 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS13190 (M5D98_13190) 2726774..2727724 - 951 WP_224688180.1 trypsin-like peptidase domain-containing protein -
M5D98_RS13195 (M5D98_13195) 2727951..2728823 + 873 WP_224688181.1 S1C family serine protease -
M5D98_RS13200 (M5D98_13200) 2728832..2729464 + 633 WP_224688182.1 helix-turn-helix transcriptional regulator -
M5D98_RS13205 (M5D98_13205) 2729583..2729846 - 264 WP_023767085.1 type II toxin-antitoxin system VapB family antitoxin -
M5D98_RS13210 (M5D98_13210) 2730025..2730891 + 867 WP_224688183.1 NAD(P)-dependent oxidoreductase -
M5D98_RS13215 (M5D98_13215) 2730888..2731181 - 294 WP_013893673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M5D98_RS13220 (M5D98_13220) 2731178..2731414 - 237 WP_224688184.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
M5D98_RS13225 (M5D98_13225) 2731876..2733345 - 1470 WP_249491007.1 OmpA family protein -
M5D98_RS13230 (M5D98_13230) 2733358..2734101 + 744 WP_249491008.1 hypothetical protein -
M5D98_RS13235 (M5D98_13235) 2734379..2734825 + 447 WP_224688218.1 YcgN family cysteine cluster protein -
M5D98_RS13240 (M5D98_13240) 2735034..2735405 + 372 WP_224688186.1 hypothetical protein -
M5D98_RS13245 (M5D98_13245) 2735610..2736320 - 711 WP_224688187.1 SIMPL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-93)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11353.24 Da        Isoelectric Point: 10.6541

>T245039 WP_013893673.1 NZ_CP097252:c2731181-2730888 [Mesorhizobium opportunistum]
MKRTVRFSPKAKADLDQIWDHSLKEWGAERAEAYIRTIRSIINLIDQFPAMAKNAENIRPGLLKYAVGSHVLFLRIADRS
IDVVRILHQRMDYPRHL

Download         Length: 294 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8664.64 Da        Isoelectric Point: 4.4367

>AT245039 WP_224688184.1 NZ_CP097252:c2731414-2731178 [Mesorhizobium opportunistum]
MPKNTSVTLGDQYDAFIQRQIANGRFGSASETVRAGLRLLEEQELKLEQLRSAIDEGDMSGGPEPFDFDAFLESKKRG

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F7YH10

Antitoxin

Source ID Structure

References