245036

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 367267..367819 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag M5D98_RS01720 Protein ID WP_224688391.1
Coordinates 367565..367819 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag M5D98_RS01715 Protein ID WP_224688296.1
Coordinates 367267..367578 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS01690 (M5D98_01690) 363240..363614 - 375 WP_224688286.1 hydroxyisourate hydrolase -
M5D98_RS01695 (M5D98_01695) 363816..365234 + 1419 WP_224688288.1 allantoinase PuuE -
M5D98_RS01700 (M5D98_01700) 365245..366108 + 864 WP_224688290.1 bifunctional allantoicase/(S)-ureidoglycine aminohydrolase -
M5D98_RS01705 (M5D98_01705) 366105..366596 + 492 WP_224688292.1 ureidoglycolate lyase -
M5D98_RS01710 (M5D98_01710) 366663..367256 + 594 WP_224688294.1 nucleoside deaminase -
M5D98_RS01715 (M5D98_01715) 367267..367578 - 312 WP_224688296.1 BrnA antitoxin family protein Antitoxin
M5D98_RS01720 (M5D98_01720) 367565..367819 - 255 WP_224688391.1 BrnT family toxin Toxin
M5D98_RS01725 (M5D98_01725) 367999..369984 + 1986 WP_224688298.1 CocE/NonD family hydrolase -
M5D98_RS01730 (M5D98_01730) 370139..371725 + 1587 WP_224688300.1 ABC transporter substrate-binding protein -
M5D98_RS01735 (M5D98_01735) 371742..372701 + 960 WP_023765585.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(28-100)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9515.15 Da        Isoelectric Point: 10.2013

>T245036 WP_224688391.1 NZ_CP097252:c367819-367565 [Mesorhizobium opportunistum]
MKIVWDEPKRVTNLKNRGLDFAELDIEFFATSTVLPAKAGRLKAIGEFGEIILAVIFKPLGFEAISVISMRRASRKERSV
YEQT

Download         Length: 255 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11685.29 Da        Isoelectric Point: 10.1359

>AT245036 WP_224688296.1 NZ_CP097252:c367578-367267 [Mesorhizobium opportunistum]
MNKPKSRIRPLTDEEEAEIQRQIAADSDDAEATDEQLARAKPFAEAFPELFESIRRARGRPPVEKPKQVVSIRLDQDVVR
KFKATGKGWQAKINEVLKNAKVS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References