Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 344382..345184 Replicon chromosome
Accession NZ_CP097252
Organism Mesorhizobium opportunistum strain WSM1558

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag M5D98_RS01610 Protein ID WP_224687828.1
Coordinates 344657..345184 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID X6CQ11
Locus tag M5D98_RS01605 Protein ID WP_023765563.1
Coordinates 344382..344660 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D98_RS01580 (M5D98_01580) 339939..340823 - 885 WP_224687824.1 DMT family transporter -
M5D98_RS01585 (M5D98_01585) 341021..341428 - 408 WP_224687825.1 DUF2000 family protein -
M5D98_RS01590 (M5D98_01590) 341476..342351 + 876 WP_224687826.1 AraC family transcriptional regulator -
M5D98_RS01595 (M5D98_01595) 342368..342838 - 471 WP_013891578.1 MarR family winged helix-turn-helix transcriptional regulator -
M5D98_RS01600 (M5D98_01600) 343255..344322 + 1068 WP_224687827.1 GTP-binding protein -
M5D98_RS01605 (M5D98_01605) 344382..344660 + 279 WP_023765563.1 DUF1778 domain-containing protein Antitoxin
M5D98_RS01610 (M5D98_01610) 344657..345184 + 528 WP_224687828.1 GNAT family N-acetyltransferase Toxin
M5D98_RS01615 (M5D98_01615) 345245..346219 + 975 WP_224687829.1 WD40 repeat domain-containing protein -
M5D98_RS01620 (M5D98_01620) 346235..346687 - 453 WP_224687830.1 hypothetical protein -
M5D98_RS01625 (M5D98_01625) 346846..348228 + 1383 WP_224687831.1 aspartate aminotransferase family protein -
M5D98_RS01630 (M5D98_01630) 348240..349640 + 1401 WP_224687832.1 glutamine synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(5-88)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18804.45 Da        Isoelectric Point: 8.3004

>T245035 WP_224687828.1 NZ_CP097252:344657-345184 [Mesorhizobium opportunistum]
VTLPSWHEEAIAKRHNRNSFDCGDTHMNDFLRRFARQSHEQNAAKTFCAVDDAAPERILGFYTIAPSAVAHENVPAAMTK
GLARHEVSGFKLARLATDLTAAGNGLGGQLLAAAALRCLRLAGEGGGILLIIDAKSERAAKWYASYGVERLQGSDLTLAM
PLATFATDLRTKGLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10107.72 Da        Isoelectric Point: 8.6585

>AT245035 WP_023765563.1 NZ_CP097252:344382-344660 [Mesorhizobium opportunistum]
MPRPADNKTERYQIRIAPAQKAMIARAAALSHQDVADFILNKVVPEAQAVIEAAEVTKVSDRDFTRILDLLEHPPKPNAK
LRAAIAALPDTL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB X6CQ11

References