Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4011139..4011284 Replicon chromosome
Accession NZ_CP097248
Organism Klebsiella pneumoniae strain NTU107224

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4011175..4011277 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4011139..4011284 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5D84_RS19460 4006269..4008329 + 2061 WP_004148850.1 oligopeptidase B -
M5D84_RS19465 4008333..4008992 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5D84_RS19470 4009071..4009301 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5D84_RS19475 4009414..4009788 + 375 WP_023285314.1 CopC domain-containing protein YobA -
M5D84_RS19480 4009792..4010661 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
M5D84_RS19485 4010678..4011016 + 339 WP_002911404.1 YebY family protein -
- 4011139..4011284 - 146 - - Antitoxin
- 4011175..4011277 + 103 - - Toxin
M5D84_RS19490 4011652..4011795 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5D84_RS19495 4011900..4012868 - 969 WP_004151446.1 VirK/YbjX family protein -
M5D84_RS19500 4013025..4013678 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
M5D84_RS19505 4013675..4013866 - 192 WP_002911395.1 YebW family protein -
M5D84_RS19510 4013964..4014203 - 240 WP_002911393.1 YebV family protein -
M5D84_RS19515 4014319..4015752 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245029 NZ_CP097248:4011175-4011277 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245029 NZ_CP097248:c4011284-4011139 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References