Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3884124..3884269 Replicon chromosome
Accession NZ_CP097237
Organism Klebsiella pneumoniae strain

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3884160..3884262 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3884124..3884269 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4268_RS18460 3879254..3881314 + 2061 WP_004151449.1 oligopeptidase B -
M4268_RS18465 3881318..3881977 - 660 WP_043906809.1 exodeoxyribonuclease X -
M4268_RS18470 3882056..3882286 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M4268_RS18475 3882399..3882773 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M4268_RS18480 3882777..3883646 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M4268_RS18485 3883663..3884001 + 339 WP_002911404.1 YebY family protein -
- 3884124..3884269 - 146 - - Antitoxin
- 3884160..3884262 + 103 - - Toxin
M4268_RS18490 3884638..3884781 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M4268_RS18495 3884886..3885854 - 969 WP_004151446.1 VirK/YbjX family protein -
M4268_RS18500 3886011..3886664 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M4268_RS18505 3886661..3886852 - 192 WP_002911395.1 YebW family protein -
M4268_RS18510 3886950..3887189 - 240 WP_002911393.1 YebV family protein -
M4268_RS18515 3887305..3888738 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T245006 NZ_CP097237:3884160-3884262 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT245006 NZ_CP097237:c3884269-3884124 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References