Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1251894..1252039 Replicon chromosome
Accession NZ_CP097232
Organism Klebsiella pneumoniae strain 4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1251901..1252003 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1251894..1252039 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4269_RS06270 1247425..1248858 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M4269_RS06275 1248974..1249213 + 240 WP_002911393.1 YebV family protein -
M4269_RS06280 1249311..1249502 + 192 WP_002911395.1 YebW family protein -
M4269_RS06285 1249499..1250152 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
M4269_RS06290 1250309..1251277 + 969 WP_004151446.1 VirK/YbjX family protein -
M4269_RS06295 1251382..1251525 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1251894..1252039 + 146 - - Antitoxin
- 1251901..1252003 - 103 - - Toxin
M4269_RS06300 1252162..1252500 - 339 WP_002911404.1 YebY family protein -
M4269_RS06305 1252517..1253386 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M4269_RS06310 1253390..1253764 - 375 WP_004151448.1 CopC domain-containing protein YobA -
M4269_RS06315 1253877..1254107 + 231 WP_002911406.1 DNA polymerase III subunit theta -
M4269_RS06320 1254186..1254845 + 660 WP_043906809.1 exodeoxyribonuclease X -
M4269_RS06325 1254849..1256909 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T244983 NZ_CP097232:c1252003-1251901 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT244983 NZ_CP097232:1251894-1252039 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References