Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1466441..1466586 Replicon chromosome
Accession NZ_CP097228
Organism Klebsiella pneumoniae strain 5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1466448..1466550 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1466441..1466586 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4270_RS07295 1461972..1463405 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M4270_RS07300 1463521..1463760 + 240 WP_002911393.1 YebV family protein -
M4270_RS07305 1463858..1464049 + 192 WP_002911395.1 YebW family protein -
M4270_RS07310 1464046..1464699 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
M4270_RS07315 1464856..1465824 + 969 WP_004151446.1 VirK/YbjX family protein -
M4270_RS07320 1465929..1466072 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1466441..1466586 + 146 - - Antitoxin
- 1466448..1466550 - 103 - - Toxin
M4270_RS07325 1466709..1467047 - 339 WP_002911404.1 YebY family protein -
M4270_RS07330 1467064..1467933 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M4270_RS07335 1467937..1468311 - 375 WP_004151448.1 CopC domain-containing protein YobA -
M4270_RS07340 1468424..1468654 + 231 WP_002911406.1 DNA polymerase III subunit theta -
M4270_RS07345 1468733..1469392 + 660 WP_043906809.1 exodeoxyribonuclease X -
M4270_RS07350 1469396..1471456 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T244966 NZ_CP097228:c1466550-1466448 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT244966 NZ_CP097228:1466441-1466586 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References