Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1472177..1472322 Replicon chromosome
Accession NZ_CP097223
Organism Klebsiella pneumoniae strain 11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1472184..1472286 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1472177..1472322 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4271_RS07320 1467708..1469141 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M4271_RS07325 1469257..1469496 + 240 WP_002911393.1 YebV family protein -
M4271_RS07330 1469594..1469785 + 192 WP_002911395.1 YebW family protein -
M4271_RS07335 1469782..1470435 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
M4271_RS07340 1470592..1471560 + 969 WP_004151446.1 VirK/YbjX family protein -
M4271_RS07345 1471665..1471808 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1472177..1472322 + 146 - - Antitoxin
- 1472184..1472286 - 103 - - Toxin
M4271_RS07350 1472445..1472783 - 339 WP_002911404.1 YebY family protein -
M4271_RS07355 1472800..1473669 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M4271_RS07360 1473673..1474047 - 375 WP_004151448.1 CopC domain-containing protein YobA -
M4271_RS07365 1474160..1474390 + 231 WP_002911406.1 DNA polymerase III subunit theta -
M4271_RS07370 1474469..1475128 + 660 WP_043906809.1 exodeoxyribonuclease X -
M4271_RS07375 1475132..1477192 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T244949 NZ_CP097223:c1472286-1472184 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT244949 NZ_CP097223:1472177-1472322 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References