Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 790852..791650 Replicon chromosome
Accession NZ_CP097213
Organism Escherichia coli strain BE311

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag M3O69_RS03840 Protein ID WP_000854899.1
Coordinates 790852..791229 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag M3O69_RS03845 Protein ID WP_001315619.1
Coordinates 791276..791650 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3O69_RS03810 (786198) 786198..787175 + 978 WP_000633209.1 type II secretion system minor pseudopilin GspK -
M3O69_RS03815 (787172) 787172..788350 + 1179 WP_000094991.1 type II secretion system protein GspL -
M3O69_RS03820 (788352) 788352..788888 + 537 WP_000942785.1 GspM family type II secretion system protein YghD -
M3O69_RS03825 (789231) 789231..790073 - 843 WP_001280533.1 DUF4942 domain-containing protein -
M3O69_RS03830 (790158) 790158..790355 - 198 WP_000839249.1 DUF957 domain-containing protein -
M3O69_RS03835 (790367) 790367..790855 - 489 WP_000779174.1 DUF5983 family protein -
M3O69_RS03840 (790852) 790852..791229 - 378 WP_000854899.1 TA system toxin CbtA family protein Toxin
M3O69_RS03845 (791276) 791276..791650 - 375 WP_001315619.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
M3O69_RS03850 (791813) 791813..792034 - 222 WP_000692311.1 DUF987 domain-containing protein -
M3O69_RS03855 (792097) 792097..792573 - 477 WP_001186770.1 RadC family protein -
M3O69_RS03860 (792589) 792589..793074 - 486 WP_000849576.1 antirestriction protein -
M3O69_RS03865 (793129) 793129..793947 - 819 WP_001234389.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(18-118)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14227.22 Da        Isoelectric Point: 6.8438

>T244908 WP_000854899.1 NZ_CP097213:c791229-790852 [Escherichia coli]
MKTLSDTHVREVSRCPSPVTIWQTLLIRLLDQHYGLTLNDTPFADECVIEQHIEAGISLCDAVNFLVEKYALVRTDQPEF
SACTRSQLINSIDILRARRATGLMTRDNYRTVNNITQGKHPEAKQ

Download         Length: 378 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 13749.53 Da        Isoelectric Point: 6.6249

>AT244908 WP_001315619.1 NZ_CP097213:c791650-791276 [Escherichia coli]
VSDKLSGITHPDDNHDRPWWGLPCTVRPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRNQHTVTLYAKGLTCEADTLGSCGYVYLAVYPAQTPATTS

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References