Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957235..1957380 Replicon chromosome
Accession NZ_CP097190
Organism Klebsiella pneumoniae strain 15-652

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1957271..1957373 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957235..1957380 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4I39_RS09440 1952365..1954425 + 2061 WP_004151449.1 oligopeptidase B -
M4I39_RS09445 1954429..1955088 - 660 WP_002911407.1 exodeoxyribonuclease X -
M4I39_RS09450 1955167..1955397 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M4I39_RS09455 1955510..1955884 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M4I39_RS09460 1955888..1956757 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M4I39_RS09465 1956774..1957112 + 339 WP_002911404.1 YebY family protein -
- 1957235..1957380 - 146 - - Antitoxin
- 1957271..1957373 + 103 - - Toxin
M4I39_RS09470 1957748..1957891 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M4I39_RS09475 1957996..1958964 - 969 WP_004151446.1 VirK/YbjX family protein -
M4I39_RS09480 1959121..1959774 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
M4I39_RS09485 1959771..1959962 - 192 WP_002911395.1 YebW family protein -
M4I39_RS09490 1960060..1960299 - 240 WP_002911393.1 YebV family protein -
M4I39_RS09495 1960415..1961848 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T244886 NZ_CP097190:1957271-1957373 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT244886 NZ_CP097190:c1957380-1957235 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References