Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 2562874..2563373 Replicon chromosome
Accession NZ_CP097186
Organism Rhodococcus sp. GA1

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag M3330_RS12015 Protein ID WP_019290516.1
Coordinates 2563119..2563373 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M3330_RS12010 Protein ID WP_019290515.1
Coordinates 2562874..2563122 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3330_RS11995 2559956..2561188 - 1233 WP_255024877.1 alpha/beta hydrolase -
M3330_RS12000 2561249..2562043 - 795 WP_006550857.1 LLM class F420-dependent oxidoreductase -
M3330_RS12005 2562509..2562649 - 141 Protein_2353 hypothetical protein -
M3330_RS12010 2562874..2563122 + 249 WP_019290515.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M3330_RS12015 2563119..2563373 + 255 WP_019290516.1 Txe/YoeB family addiction module toxin Toxin
M3330_RS12020 2563474..2563995 - 522 WP_200359089.1 hypothetical protein -
M3330_RS12025 2564152..2565108 + 957 WP_255028899.1 ERCC4 domain-containing protein -
M3330_RS12030 2565476..2565664 + 189 WP_019290519.1 hypothetical protein -
M3330_RS12035 2565671..2565883 + 213 WP_019290520.1 hypothetical protein -
M3330_RS12040 2566041..2566667 - 627 WP_006550849.1 TetR family transcriptional regulator -
M3330_RS12045 2566770..2567939 + 1170 WP_019290521.1 acyl-CoA dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10078.37 Da        Isoelectric Point: 6.7171

>T244882 WP_019290516.1 NZ_CP097186:2563119-2563373 [Rhodococcus sp. GA1]
VNITFTDEAWDDYQFWISTDRKQLERVNELIRDCQRDPYSGIGKPERLRHALSGLWSRRIDKEHRLVYEVIDGALVIIAA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9264.55 Da        Isoelectric Point: 6.4661

>AT244882 WP_019290515.1 NZ_CP097186:2562874-2563122 [Rhodococcus sp. GA1]
MAAITATEARKNFFPLLEQVNKDHTPVEIVSKRGNAVLMSKDDYDAMLETSYLMQSPANARRLLASMQRARGGEHTEREL
IE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References