Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4427394..4427891 | Replicon | chromosome |
Accession | NZ_CP097170 | ||
Organism | Escherichia coli strain AR13438 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | M3M51_RS21350 | Protein ID | WP_001173343.1 |
Coordinates | 4427394..4427567 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | L4JK92 |
Locus tag | M3M51_RS21355 | Protein ID | WP_000398619.1 |
Coordinates | 4427595..4427891 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M3M51_RS21340 (4424064) | 4424064..4425521 | + | 1458 | WP_061092757.1 | dipeptide/tripeptide permease DtpC | - |
M3M51_RS21345 (4425758) | 4425758..4427275 | + | 1518 | WP_000003806.1 | lysine--tRNA ligase | - |
M3M51_RS21350 (4427394) | 4427394..4427567 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
M3M51_RS21355 (4427595) | 4427595..4427891 | - | 297 | WP_000398619.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
M3M51_RS21360 (4428120) | 4428120..4428392 | - | 273 | WP_000405647.1 | GNAT family N-acetyltransferase | - |
M3M51_RS21365 (4428404) | 4428404..4428634 | - | 231 | WP_000371704.1 | 4Fe-4S mono-cluster protein YjdI | - |
M3M51_RS21370 (4428815) | 4428815..4430446 | + | 1632 | WP_061092758.1 | sensor histidine kinase | - |
M3M51_RS21375 (4430443) | 4430443..4431162 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QBH6 |