Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3007906..3008537 Replicon chromosome
Accession NZ_CP097128
Organism Conexibacter sp. DBS9H8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M3M55_RS14350 Protein ID WP_249010185.1
Coordinates 3007906..3008292 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M3M55_RS14355 Protein ID WP_249010186.1
Coordinates 3008289..3008537 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M55_RS14325 3003090..3004502 + 1413 WP_249010180.1 MBL fold metallo-hydrolase -
M3M55_RS14330 3004590..3005045 - 456 WP_249010181.1 ester cyclase -
M3M55_RS14335 3005103..3005789 - 687 WP_249010182.1 metalloregulator ArsR/SmtB family transcription factor -
M3M55_RS14340 3005820..3007106 + 1287 WP_249010183.1 MFS transporter -
M3M55_RS14345 3007432..3007665 + 234 WP_249010184.1 hypothetical protein -
M3M55_RS14350 3007906..3008292 - 387 WP_249010185.1 type II toxin-antitoxin system VapC family toxin Toxin
M3M55_RS14355 3008289..3008537 - 249 WP_249010186.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
M3M55_RS14365 3008831..3009907 - 1077 WP_249010187.1 FTR1 family protein -
M3M55_RS14370 3010041..3010940 + 900 WP_249010188.1 PHP domain-containing protein -
M3M55_RS14375 3010969..3011619 - 651 WP_249010189.1 RNA polymerase sporulation sigma factor SigH -
M3M55_RS14380 3011945..3012631 - 687 WP_249010190.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Antitoxin VapB-like

(2-81)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 12963.75 Da        Isoelectric Point: 4.5873

>T244820 WP_249010185.1 NZ_CP097128:c3008292-3007906 [Conexibacter sp. DBS9H8]
MIAVDSSALIAVVLGEADAERFLAAMGADAASLSAVSLTEATIVAEARQGADAVRDLELLVAGVIDRVVAVDATHARAAA
AAWRRFGKGRHPAGLNLGDCFAYATASLAGAPLLFKGNDFAQTDLPAA

Download         Length: 387 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8753.84 Da        Isoelectric Point: 4.8011

>AT244820 WP_249010186.1 NZ_CP097128:c3008537-3008289 [Conexibacter sp. DBS9H8]
VALNIKDPETDRLARELADLSGQSITTAVREALEERIAVLTARARASGPGLDGIISRGRARSILDDRSPEEILGYGADGL
PR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References