Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 890446..891103 Replicon chromosome
Accession NZ_CP097128
Organism Conexibacter sp. DBS9H8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M3M55_RS04240 Protein ID WP_249011579.1
Coordinates 890446..890850 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M3M55_RS04245 Protein ID WP_249011580.1
Coordinates 890840..891103 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M55_RS04220 886561..887868 + 1308 WP_249011576.1 biotin/lipoyl-binding protein -
M3M55_RS04225 887960..888643 + 684 WP_249012444.1 ABC transporter ATP-binding protein -
M3M55_RS04230 888640..889872 + 1233 WP_249011577.1 ABC transporter permease -
M3M55_RS04235 890064..890351 + 288 WP_249011578.1 DUF2283 domain-containing protein -
M3M55_RS04240 890446..890850 - 405 WP_249011579.1 type II toxin-antitoxin system VapC family toxin Toxin
M3M55_RS04245 890840..891103 - 264 WP_249011580.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M3M55_RS04250 891257..891667 - 411 WP_249011581.1 type II toxin-antitoxin system death-on-curing family toxin -
M3M55_RS04255 891664..891915 - 252 WP_249011582.1 hypothetical protein -
M3M55_RS04260 892047..892415 + 369 WP_249011583.1 metalloregulator ArsR/SmtB family transcription factor -
M3M55_RS04265 893031..893654 + 624 WP_249011584.1 DUF1778 domain-containing protein -
M3M55_RS04270 893647..894165 + 519 WP_249011585.1 GNAT family N-acetyltransferase -
M3M55_RS04275 894263..894655 - 393 WP_256469069.1 PIN domain-containing protein -
M3M55_RS04280 894652..894900 - 249 WP_249011587.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-46)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14727.94 Da        Isoelectric Point: 11.0408

>T244818 WP_249011579.1 NZ_CP097128:c890850-890446 [Conexibacter sp. DBS9H8]
MSADRRLSYLDSSAIVKLVIQEPESSALRRHLSRRQPVVSSALARTEVARALLPSGPEALARGEQVLRRIQLLRVNDRVL
DQAGPLEPPELRALDAIHLASAHQLGVSVRQIVTYDHRMADAARSLGWTVIAPS

Download         Length: 405 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9399.64 Da        Isoelectric Point: 4.5112

>AT244818 WP_249011580.1 NZ_CP097128:c891103-890840 [Conexibacter sp. DBS9H8]
VGVRELRQRASELLRLVESGESIEITDRGRPVAILGPLPEDPLERLRASGDLQAADGELADLPDPLPPPASSALPSSVLA
RLRRDER

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References