Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3341425..3342170 Replicon chromosome
Accession NZ_CP097127
Organism Conexibacter sp. S30A1

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag M3M54_RS16005 Protein ID WP_249020021.1
Coordinates 3341673..3342170 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag M3M54_RS16000 Protein ID WP_249020020.1
Coordinates 3341425..3341676 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M54_RS15965 3336774..3337565 - 792 WP_249020014.1 sigma-70 family RNA polymerase sigma factor -
M3M54_RS15970 3337611..3337832 + 222 WP_249020015.1 DUF2892 domain-containing protein -
M3M54_RS15975 3337937..3338875 + 939 WP_249021793.1 ATP-binding cassette domain-containing protein -
M3M54_RS15980 3338872..3339636 + 765 WP_249020016.1 ABC transporter permease -
M3M54_RS15985 3339740..3340165 + 426 WP_249020017.1 hypothetical protein -
M3M54_RS15990 3340162..3340635 + 474 WP_249020018.1 MarR family winged helix-turn-helix transcriptional regulator -
M3M54_RS15995 3340911..3341255 + 345 WP_249020019.1 hypothetical protein -
M3M54_RS16000 3341425..3341676 + 252 WP_249020020.1 DUF1778 domain-containing protein Antitoxin
M3M54_RS16005 3341673..3342170 + 498 WP_249020021.1 GNAT family N-acetyltransferase Toxin
M3M54_RS16010 3342426..3342596 - 171 WP_249020022.1 hypothetical protein -
M3M54_RS16015 3343006..3343302 - 297 WP_249020023.1 hypothetical protein -
M3M54_RS16020 3343289..3343546 - 258 WP_249020024.1 hypothetical protein -
M3M54_RS16030 3343888..3344352 - 465 WP_249020025.1 tRNA adenosine(34) deaminase TadA -
M3M54_RS16035 3344506..3346137 + 1632 WP_249020026.1 S8 family serine peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-72)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18065.74 Da        Isoelectric Point: 10.3226

>T244814 WP_249020021.1 NZ_CP097127:3341673-3342170 [Conexibacter sp. S30A1]
MSDLRIGPLERGHQLEAFASGADELDRWLHRFARVADASGTAKTYVLANGNRVLGYYALTPAAVNRHELPERHAKGMPAR
PIGVILLARLAVDGSFQGQGYGRALMADAAIRTLQAADLVGARAMLVHARDERAASFYERLGFTRSPTDALHLMVLIKDL
RRTFG

Download         Length: 498 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9321.51 Da        Isoelectric Point: 5.2169

>AT244814 WP_249020020.1 NZ_CP097127:3341425-3341676 [Conexibacter sp. S30A1]
MNLRLAEEADDRIRRAAAASGVSTSAFVERAASVAADKVLADRREFVLDSEAWDRFVAELDRPAKDLPELRRGRELRDRL
IAP

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References