244805

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 1066098..1066764 Replicon chromosome
Accession NZ_CP097127
Organism Conexibacter sp. S30A1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M3M54_RS05325 Protein ID WP_249021151.1
Coordinates 1066098..1066502 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M3M54_RS05330 Protein ID WP_249021152.1
Coordinates 1066492..1066764 (-) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M54_RS05295 1062545..1063147 - 603 WP_249021145.1 biotin transporter BioY -
M3M54_RS05300 1063218..1063709 - 492 WP_249021146.1 GNAT family N-acetyltransferase -
M3M54_RS05305 1064192..1064467 + 276 WP_249021147.1 hypothetical protein -
M3M54_RS05310 1064478..1064642 + 165 WP_249021148.1 hypothetical protein -
M3M54_RS05315 1064736..1064975 - 240 WP_249021149.1 hypothetical protein -
M3M54_RS05320 1065270..1065794 + 525 WP_249021150.1 2'-5' RNA ligase family protein -
M3M54_RS05325 1066098..1066502 - 405 WP_249021151.1 type II toxin-antitoxin system VapC family toxin Toxin
M3M54_RS05330 1066492..1066764 - 273 WP_249021152.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M3M54_RS05335 1066838..1066993 + 156 WP_249021153.1 hypothetical protein -
M3M54_RS05340 1067247..1067825 + 579 WP_249021154.1 GNAT family protein -
M3M54_RS05345 1067971..1068171 + 201 WP_249021155.1 hypothetical protein -
M3M54_RS05350 1068177..1068605 - 429 WP_249021156.1 PIN domain-containing protein -
M3M54_RS05355 1068602..1068874 - 273 WP_249021157.1 hypothetical protein -
M3M54_RS05360 1069088..1069468 - 381 WP_249021158.1 Fic family protein -
M3M54_RS05365 1069465..1069656 - 192 WP_249021159.1 hypothetical protein -
M3M54_RS05370 1070146..1070730 + 585 WP_249019413.1 DUF6431 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-123)

Antitoxin

(1-49)


Sequences


Toxin        


Download         Length: 135 a.a.        Molecular weight: 14632.79 Da        Isoelectric Point: 11.1839

>T244805 WP_249021151.1 NZ_CP097127:c1066502-1066098 [Conexibacter sp. S30A1]
MSADQRLTYVDSSAIVKLAIQEPESSALRRHLSRHQPLVSSALARTEVARALLPSGPAALARGEQVLRRIQLLRVNDRVL
NEAGRLKPPELRSLDAIHLASAHQLGASVRQIVTYDDRMADAARTLGWTVVAPS

Download         Length: 405 bp


Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9815.97 Da        Isoelectric Point: 4.4463

>AT244805 WP_249021152.1 NZ_CP097127:c1066764-1066492 [Conexibacter sp. S30A1]
MTSVGVRELRQRASELLRRVESGESIEITDRGRPVAMLGPLPEDPLDRLRASGDLQEAEGDLSDLPDPLPAPAGSESPSS
VLARLRRDER

Download         Length: 273 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References