Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 4045744..4046320 Replicon chromosome
Accession NZ_CP097107
Organism Citrobacter freundii strain GMU8049

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag M3L74_RS20240 Protein ID WP_003837215.1
Coordinates 4046033..4046320 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag M3L74_RS20235 Protein ID WP_003837217.1
Coordinates 4045744..4046046 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3L74_RS20220 (4042256) 4042256..4044406 + 2151 WP_088902764.1 pyruvate/proton symporter BtsT -
M3L74_RS20225 (4044517) 4044517..4044711 + 195 WP_003830038.1 YbdD/YjiX family protein -
M3L74_RS20230 (4044724) 4044724..4045680 + 957 WP_088902765.1 GTPase -
M3L74_RS20235 (4045744) 4045744..4046046 - 303 WP_003837217.1 BrnA antitoxin family protein Antitoxin
M3L74_RS20240 (4046033) 4046033..4046320 - 288 WP_003837215.1 BrnT family toxin Toxin
M3L74_RS20245 (4046555) 4046555..4047721 + 1167 WP_088902766.1 restriction endonuclease -
M3L74_RS20250 (4047817) 4047817..4050246 + 2430 WP_088902767.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(39-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.50 Da        Isoelectric Point: 7.0746

>T244793 WP_003837215.1 NZ_CP097107:c4046320-4046033 [Citrobacter freundii]
MPMEFEWDANKAQSNLRKHGVRFEDAVLVFDDPQHLSRQDRHENGEYRWQTIGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADSKERSRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11513.16 Da        Isoelectric Point: 10.1293

>AT244793 WP_003837217.1 NZ_CP097107:c4046046-4045744 [Citrobacter freundii]
MNMVKHKRGSISALSAQHEAELKALANKPDDDIDYSDIPVTEDKQWSEATRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References