Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1907048..1907190 Replicon chromosome
Accession NZ_CP097107
Organism Citrobacter freundii strain GMU8049

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1907083..1907186 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1907048..1907190 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3L74_RS09700 1902201..1903103 - 903 WP_003844140.1 diguanylate cyclase -
M3L74_RS09705 1903421..1903612 - 192 WP_008322661.1 hypothetical protein -
M3L74_RS09710 1904105..1904695 - 591 WP_032939142.1 hypothetical protein -
M3L74_RS09715 1904850..1905059 + 210 WP_003844137.1 hypothetical protein -
M3L74_RS09720 1905318..1905692 + 375 WP_044711069.1 CopC domain-containing protein YobA -
M3L74_RS09725 1905696..1906568 + 873 WP_049002332.1 copper homeostasis membrane protein CopD -
M3L74_RS09730 1906589..1906927 + 339 WP_003833793.1 YebY family protein -
- 1907048..1907190 - 143 - - Antitoxin
- 1907083..1907186 + 104 - - Toxin
M3L74_RS09735 1907264..1908349 - 1086 WP_249018434.1 phage integrase Arm DNA-binding domain-containing protein -
M3L74_RS09740 1908318..1908590 - 273 WP_071684411.1 excisionase -
M3L74_RS09745 1908654..1908896 - 243 WP_019076930.1 DUF4060 family protein -
M3L74_RS09750 1908883..1909536 - 654 WP_249018535.1 hypothetical protein -
M3L74_RS09755 1909595..1910707 - 1113 WP_181630814.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1894171..1959373 65202


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T244787 NZ_CP097107:1907083-1907186 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 143 bp

>AT244787 NZ_CP097107:c1907190-1907048 [Citrobacter freundii]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References